Synthesis of a novel class of benzofurans via a three-component, regiospecific intramolecular heterocylization reaction

被引：34
|
作者：
Karami, Bahador [1 ]
Khodabakhshi, Saeed [1 ]
Hashemi, Fatemeh [1 ]
机构：
[1] Univ Yasuj, Dept Chem, Yasuj 7591874831, Iran
来源：
TETRAHEDRON LETTERS | 2013年 / 54卷 / 28期
关键词：
Benzofuran; Arylglyoxal; Phenol; Benzamide; Three-component; RING-CLOSING METATHESIS; SOLVENT-FREE CONDITIONS; TUNGSTIC ACID STA; ONE-POT; RAPID SYNTHESIS; DERIVATIVES; PHENOLS; CATALYST; CHLORIDE; ANALOGS;
D O I：
10.1016/j.tetlet.2013.03.124
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new, convenient, and environmentally benign three-component synthesis of a novel class of benzofurans is developed by condensing different arylglyoxals, benzamide, and phenolic substrates under solvent-free conditions. These reactions are catalyzed by tungstate sulfuric acid (TSA) as a safe, clean, and recyclable solid acid. The method is operationally simple and provides access to a variety of 2-aryl-3-benzamido benzofurans in good to excellent yields. (C) 2013 Published by Elsevier Ltd.
引用
收藏
页码：3583 / 3585
页数：3
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