High yield production of [18F]MK-6240 on the AllinOne synthesizer, a promising PET Tracer for the quantification of Human Neurofibrillary tangles in Alzheimer disease

被引:0
|
作者
Vriamont, Charles [1 ]
Otabashi, Muhammad [1 ]
Warnier, Corentin [1 ]
机构
[1] Trasis, Ans, Belgium
关键词
D O I
暂无
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
1039
引用
收藏
页数:2
相关论文
共 45 条
  • [31] [18F] MK-6240 for imaging tau in patients with Alzheimer's disease: Longitudinal evaluation in Alzheimer's disease and cognitively normal adults at 6 and 12 months
    Salinas, C. A.
    Purohit, A.
    Beaver, J.
    Martarello, L.
    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2019, 39 : 12 - 13
  • [32] The spatial extent of tauopathy on [18F]MK-6240 tau PET shows stronger association with cognitive performances than the standard uptake value ratio in Alzheimer’s disease
    Thomas Gérard
    Lise Colmant
    Vincent Malotaux
    Yasmine Salman
    Lara Huyghe
    Lisa Quenon
    Laurence Dricot
    Adrian Ivanoiu
    Renaud Lhommel
    Bernard Hanseeuw
    European Journal of Nuclear Medicine and Molecular Imaging, 2024, 51 : 1662 - 1674
  • [33] The spatial extent of tauopathy on [18F]MK-6240 tau PET shows stronger association with cognitive performances than the standard uptake value ratio in Alzheimer's disease
    Gerard, Thomas
    Colmant, Lise
    Malotaux, Vincent
    Salman, Yasmine
    Huyghe, Lara
    Quenon, Lisa
    Dricot, Laurence
    Ivanoiu, Adrian
    Lhommel, Renaud
    Hanseeuw, Bernard
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2024, 51 (06) : 1662 - 1674
  • [34] Discovery of 6-(Fluoro-18F)-3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinolin-5-amine ([18F}-MK-6240): A Positron Emission Tomography (PET) Imaging Agent for Quantification of Neurofibrillary Tangles (NFTs)
    Walji, Abbas M.
    Hostetler, Eric D.
    Selnick, Harold
    Zeng, Zhizhen
    Miller, Patricia
    Bennacef, Idriss
    Salinas, Cristian
    Connolly, Brett
    Gantert, Liza
    Holahan, Marie
    O'Malley, Stacey
    Purcell, Mona
    Riffel, Kerry
    Li, Jin
    Balsells, Jaume
    OBrien, Julie A.
    Melquist, Stacey
    Soriano, Aileen
    Zhang, Xiaoping
    Ogawa, Aimie
    Xu, Serena
    Joshi, Elizabeth
    Della Rocca, Joseph
    Hess, Fred J.
    Schachter, Joel
    Hesk, David
    Schenk, David
    Struyk, Arie
    Babaoglu, Kerim
    Lohith, Talakad G.
    Wang, Yaode
    Yang, Kun
    Fu, Jianmin
    Evelhoch, Jeffrey L.
    Coleman, Paul J.
    JOURNAL OF MEDICINAL CHEMISTRY, 2016, 59 (10) : 4778 - 4789
  • [35] Monte-Carlo Simulations for Evaluating Sensitivity of Tau Detection in [F-18]MK-6240 PET Scans of Early Stage Alzheimer's Disease
    McVea, Andrew
    Betthauser, Tobey
    Zammit, Matthew
    Tullis, Tyler
    DiFilippo, Alexandra
    Johnson, Sterling
    Christian, Bradley
    JOURNAL OF NUCLEAR MEDICINE, 2020, 61
  • [36] PET simulations investigating the effect of off-target binding in [F-18]MK-6240 PET scans for the detection of early-stage Alzheimer's disease
    Mcvea, Andrew
    DiFilippo, Alexandra
    McLachlan, Max
    Xin, Yangchun
    Johnson, Sterling
    Betthauser, Tobey
    Christian, Bradley
    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2021, 41 (1_SUPPL): : 98 - 99
  • [37] Evaluation of a novel PET tracer [18F]-Florbetazine for Alzheimer's disease diagnosis and (3-amyloid deposition quantification
    Wu, Meiqi
    Ren, Chao
    Mao, Chenhui
    Dong, Liling
    Li, Bo
    Yang, Xueqian
    Huang, Zhenghai
    Zhang, Haiqiong
    Li, Yuying
    Yan, Mengshi
    Ge, Qi
    Wu, Runze
    Feng, Feng
    Cui, Mengchao
    Gao, Jing
    Huo, Li
    NEUROIMAGE, 2024, 298
  • [38] Tau deposition assessed by [18F]MK6240 PET is associated with longitudinal decrease in grey matter density across the spectrum of Alzheimer's disease
    Lussier, Firoza Z.
    Pascoal, Tharick A.
    Therriault, Joseph
    Benedet, Andrea L.
    Tissot, Cecile
    Wang, Yi-Ting
    Arias, Jaime F.
    Savard, Melissa
    Gauthier, Serge
    Rosa-Neto, Pedro
    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2021, 41 (1_SUPPL): : 261 - 261
  • [39] [11C]MK-6884 PET Tracer for M4 Muscarinic Cholinergic Receptors in Alzheimer's Disease: Comparison with [18F]FDG PET
    Masdeu, Joseph
    Pascual, Belen
    Zanotti-Fregonara, Paolo
    Yu, Meixiang
    Funk, Quentin
    Arbones, Victoria
    Rockers, Elijah
    Wang, Yuchuan
    Li, Wenping
    Cheng, Amy
    Anderson, Matt
    Hostetler, Eric
    Basile, Anthony
    NEUROLOGY, 2020, 94 (15)
  • [40] Development and Identification of [18F]SNFT-1 (THK-5562), a Promising Candidate for Selective Tau PET Tracer in Alzheimer's disease
    Lerdsirisuk, P.
    Harada, R.
    Shimizu, Y.
    Du, Y.
    Ishikawa, Y.
    Iwata, R.
    Yanai, K.
    Kudo, Y.
    Okamura, N.
    Furumoto, S.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2020, 47 (SUPPL 1) : S115 - S115