High yield production of [18F]MK-6240 on the AllinOne synthesizer, a promising PET Tracer for the quantification of Human Neurofibrillary tangles in Alzheimer disease

被引:0
|
作者
Vriamont, Charles [1 ]
Otabashi, Muhammad [1 ]
Warnier, Corentin [1 ]
机构
[1] Trasis, Ans, Belgium
关键词
D O I
暂无
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
1039
引用
收藏
页数:2
相关论文
共 45 条
  • [21] High resolution autoradiography of [18F]MK-6240 and [18F]Flortaucipir shows similar neurofibrillary tangle binding patterns preferentially recognizing middling neurofibrillary tangle maturity
    Ghatamaneni, Sujala
    Hruska, Courtney
    Shin, Ian
    Bruinsma, Tyler
    Scott, Nancy
    Lee, Jeyeon
    Fang, Ping
    Min, Hoon-Ki
    Moloney, Christina M.
    Wood, Ashley C.
    Constantopoulos, Eleni
    Reichard, Ross R.
    Schwarz, Christopher G.
    Jones, David T.
    Graff-Radford, Jonathan
    Knopman, David S.
    Jack Jr, Clifford R.
    Petersen, Ronald C.
    Dickson, Dennis W.
    Murray, Melissa E.
    Lowe, Val J.
    ACTA NEUROPATHOLOGICA, 2025, 149 (01)
  • [22] [18F]MK-6240 PET identifies neurofibrillary tangle pathology in prodromal alzhiemer's disease patients from a phase 3 (APECS) trial
    Lohith, T. G.
    Sur, C.
    Taylor, T.
    Dupre, N.
    Kost, J.
    Adamczuk, K.
    Hostetler, E.
    Evelhoch, J.
    Voss, T.
    Egan, M.
    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2019, 39 : 560 - 561
  • [23] High-yield fully automated production of [18F] Fluorocholine at high activity on the AllinOne Synthesizer
    Otabashi, Muhammad
    Vergote, Thomas
    Desfours, Caroline
    Morelle, Jean-Luc
    Philippart, Gauthier
    JOURNAL OF NUCLEAR MEDICINE, 2017, 58
  • [24] HIGH-YIELD FULLY AUTOMATED PRODUCTION OF [18F] FLUOROCHOLINE AT HIGH ACTIVITY ON THE AllinOne SYNTHESIZER
    Otabashi, M.
    Desfours, C.
    Vergote, T.
    Morelle, J-L
    Philippart, G.
    INTERNAL MEDICINE JOURNAL, 2017, 47 : 11 - 11
  • [25] Autoradiography validation of novel tau PET tracer [F-18]-MK-6240 on human postmortem brain tissue
    Aguero, Cinthya
    Dhaynaut, Maeva
    Normandin, Marc D.
    Amaral, Ana C.
    Guehl, Nicolas J.
    Neelamegam, Ramesh
    Marquie, Marta
    Johnson, Keith A.
    El Fakhri, Georges
    Frosch, Matthew P.
    Gomez-Isla, Teresa
    ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2019, 7 (1) : 37
  • [26] Autoradiography validation of novel tau PET tracer [F-18]-MK-6240 on human postmortem brain tissue
    Cinthya Aguero
    Maeva Dhaynaut
    Marc D. Normandin
    Ana C. Amaral
    Nicolas J. Guehl
    Ramesh Neelamegam
    Marta Marquie
    Keith A. Johnson
    Georges El Fakhri
    Matthew P. Frosch
    Teresa Gomez-Isla
    Acta Neuropathologica Communications, 7
  • [27] Development of [18F]FAZIN3 for PET imaging of neurofibrillary tangles in Alzheimer's Disease
    Liang, Christopher
    Phuc Lam
    Martinez, Stephanie
    Mukherjee, Jogeshwar
    JOURNAL OF NUCLEAR MEDICINE, 2020, 61
  • [28] Dual-time-window dynamic [18F]MK-6240 PET protocols for improved quantification in longitudinal studies and stroke patients
    Kolinger, G. D.
    Garcia, D. Vallez
    Boellaard, R.
    Lohith, T. G.
    Hostetler, E. D.
    Sur, C.
    Struyk, A.
    Koole, M.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2020, 47 (SUPPL 1) : S167 - S167
  • [29] In Vivo Characterization and Quantification of Neurofibrillary Tau PET Radioligand 18F-MK-6240 in Humans from Alzheimer Disease Dementia to Young Controls
    Betthauser, Tobey J.
    Cody, Karly A.
    Zammit, Matthew D.
    Murali, Dhanabalan
    Converse, Alexander K.
    Barnhart, Todd E.
    Stone, Charles K.
    Rowley, Howard A.
    Johnson, Sterling C.
    Christian, Bradley T.
    JOURNAL OF NUCLEAR MEDICINE, 2019, 60 (01) : 93 - 99
  • [30] Test-retest characteristic of [18F]MK-6240 quantitative outcomes in cognitively normal adults and subjects with Alzheimer's disease
    Salinas, Cristian
    Lohith, Talakad G.
    Purohit, Ajay
    Struyk, Arie
    Sur, Cyrille
    Bennacef, Idriss
    Beaver, John
    Martarello, Laurent
    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2020, 40 (11): : 2179 - 2187