Analysis of intraoperative complication of ruptured cerebral aneurysm with detachable coils embolization

Objective: To report the incidence of intraoperative complications of coiling of ruptured cerebral aneurysms leading to permanent disability or death in a consecutive series of 341 patients and to identify risk factors for these events. Methods: Between January 2007 and May 2011, 341 consecutive patients with ruptured intracranial aneurysms were treated with detachable coils. Procedural complications of coils embolization leading to death or neurologic disability at the time of hospital discharge were recorded. For patients with procedural complications, odds ratios (OR) with corresponding 95% confidence intervals (CI) were calculated for the following patient and aneurysm characteristics: patient age and sex, use of a supporting balloon, aneurysm location, timing of treatment, clinical condition at the time of treatment, and aneurysm size. Results: Procedural complications occurred in 21 of 341 patients (6.16%; 95% CI, 4.2% to 8.1%), leading to death in 9 patients (procedural mortality, 2.6%; 95% CI, 1.6% to 4.2%) and to disability in 12 patients (procedural morbidity, 3.5%; 95% CI, 2.0% to 5.3%). There were 4 procedural ruptures and 17 thrombotic complications. The significant risk factors for the occurrence of procedural complications were use of supporting balloon (OR, 5.3; 95% CI, 2.3 to 16.1%) and stent (OR, 8.4; 95% CI, 4.1 to 20.5%). Conclusion: Procedural complication rate of coiling of ruptured aneurysms leading to disability or death is 6.16%. In this series, the use of a temporary supporting balloon and stent in the treatment of wide-necked aneurysms was the risk factors for the occurrence of complications. [Analysis of intraoperative complication of ruptured cerebral aneurysm with detachable coils embolization. Life Science Journal. 2011; 8(3):543-546] (ISSN: 1097-8135). http://www.lifesciencesite.com.