Interventions for Prevention and Control of Epidemic of Vitamin D Deficiency

被引:7
|
作者
Marwaha, Raman Kumar [1 ,2 ,3 ]
Dabas, Aashima [4 ]
机构
[1] Int Life Sci Inst, New Delhi, India
[2] Soc Endocrine Hlth Care Elderly Adolescents & Chi, New Delhi, India
[3] Flat 17,Gautam Apartments, New Delhi 110049, India
[4] Maulana Azad Med Coll & Associated Lok Nayak Hosp, Dept Pediat, New Delhi, India
来源
INDIAN JOURNAL OF PEDIATRICS | 2019年 / 86卷 / 06期
关键词
Sunlight; Vitamin D supplementation; Fortification; 25(OH)D; India; RANDOMIZED CLINICAL-TRIAL; D SUPPLEMENTATION; 25-HYDROXYVITAMIN D; ORAL CHOLECALCIFEROL; CALCIUM DEFICIENCY; SERUM 25(OH)D; CHILDREN; PREGNANCY; IMPACT; ADOLESCENTS;
D O I
10.1007/s12098-019-02857-z
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Vitamin D deficiency (VDD) remains a significant health challenge globally with its overwhelming effects on skeletal growth and varied associations with extra-skeletal diseases. The last decade has reported a high prevalence of VDD in all age-groups across all zones of India. Children and adolescents are most vulnerable to ill-effects of VDD as peak linear growth and bone mass accrual occurs during these years. Vitamin D deficiency in mothers predisposes their infants to have low serum vitamin D levels. Indians have increased susceptibility to develop VDD due to predominant vegetarian dietary habits, high melanin skin content, atmospheric pollution, modest tradition of clothing and limited availability of fortified foods. Vitamin D supplementation during infancy and childhood has emerged as an effective strategy to combat VDD. However, effects of vitamin D supplementation are transient and are not cost-effective as a maintenance strategy. Fortification of foodstuffs has been adopted by many developed countries globally which has emerged as a safe, efficacious and cost-effective strategy to control VDD. A strong political will and support is required to sustain food fortification in India. The current review focuses on strategies to prevent and control the epidemic of VDD in children.
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页码:532 / 537
页数:6
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