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Interventions for Prevention and Control of Epidemic of Vitamin D Deficiency
被引:7
|作者:
Marwaha, Raman Kumar
[1
,2
,3
]
Dabas, Aashima
[4
]
机构:
[1] Int Life Sci Inst, New Delhi, India
[2] Soc Endocrine Hlth Care Elderly Adolescents & Chi, New Delhi, India
[3] Flat 17,Gautam Apartments, New Delhi 110049, India
[4] Maulana Azad Med Coll & Associated Lok Nayak Hosp, Dept Pediat, New Delhi, India
来源:
关键词:
Sunlight;
Vitamin D supplementation;
Fortification;
25(OH)D;
India;
RANDOMIZED CLINICAL-TRIAL;
D SUPPLEMENTATION;
25-HYDROXYVITAMIN D;
ORAL CHOLECALCIFEROL;
CALCIUM DEFICIENCY;
SERUM 25(OH)D;
CHILDREN;
PREGNANCY;
IMPACT;
ADOLESCENTS;
D O I:
10.1007/s12098-019-02857-z
中图分类号:
R72 [儿科学];
学科分类号:
100202 ;
摘要:
Vitamin D deficiency (VDD) remains a significant health challenge globally with its overwhelming effects on skeletal growth and varied associations with extra-skeletal diseases. The last decade has reported a high prevalence of VDD in all age-groups across all zones of India. Children and adolescents are most vulnerable to ill-effects of VDD as peak linear growth and bone mass accrual occurs during these years. Vitamin D deficiency in mothers predisposes their infants to have low serum vitamin D levels. Indians have increased susceptibility to develop VDD due to predominant vegetarian dietary habits, high melanin skin content, atmospheric pollution, modest tradition of clothing and limited availability of fortified foods. Vitamin D supplementation during infancy and childhood has emerged as an effective strategy to combat VDD. However, effects of vitamin D supplementation are transient and are not cost-effective as a maintenance strategy. Fortification of foodstuffs has been adopted by many developed countries globally which has emerged as a safe, efficacious and cost-effective strategy to control VDD. A strong political will and support is required to sustain food fortification in India. The current review focuses on strategies to prevent and control the epidemic of VDD in children.
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页码:532 / 537
页数:6
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