Novel treatment strategies for aggressive non-Hodgkin's lymphoma

被引:5
|
作者
Fayad, L [1 ]
Younes, A [1 ]
机构
[1] Univ Texas, MD Anderson Canc Ctr, Dept Lymphoma Myeloma, Houston, TX 77030 USA
关键词
Akt; aurora; BAFF; CD40; Hsp-90; HDAC; mTOR; PLK; TRAIL;
D O I
10.1517/14656566.7.6.733
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The World Health Organization has included different types of lymphoma under the aggressive category. In the US, diffuse large B-cell lymphoma is the most common aggressive lymphoma and accounts for > 30% of the 55,000 new cases diagnosed annually. Recent advances in the knowledge of the molecular biology have provided an increased understanding of the heterogeneity of non-Hodgkin's lymphoma. New treatments, especially those with the use of monoclonal antibodies, are improving both the survival and the response rate.
引用
收藏
页码:733 / 748
页数:16
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