Novel treatment strategies for aggressive non-Hodgkin's lymphoma

被引:5
|
作者
Fayad, L [1 ]
Younes, A [1 ]
机构
[1] Univ Texas, MD Anderson Canc Ctr, Dept Lymphoma Myeloma, Houston, TX 77030 USA
关键词
Akt; aurora; BAFF; CD40; Hsp-90; HDAC; mTOR; PLK; TRAIL;
D O I
10.1517/14656566.7.6.733
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The World Health Organization has included different types of lymphoma under the aggressive category. In the US, diffuse large B-cell lymphoma is the most common aggressive lymphoma and accounts for > 30% of the 55,000 new cases diagnosed annually. Recent advances in the knowledge of the molecular biology have provided an increased understanding of the heterogeneity of non-Hodgkin's lymphoma. New treatments, especially those with the use of monoclonal antibodies, are improving both the survival and the response rate.
引用
收藏
页码:733 / 748
页数:16
相关论文
共 50 条
  • [21] Therapy strategies for aggressive non-Hodgkin’s lymphoma [Therapiestrategien der aggressiven Non-Hodgkin-Lymphome]
    Held G.
    Wulf G.
    Der Onkologe, 2015, 21 (10): : 946 - 952
  • [22] Treatment of non-Hodgkin's lymphoma
    Dranitsaris, G
    ANTI-CANCER DRUGS, 1998, 9 (10) : 879 - 888
  • [23] Treatment of aggressive non-Hodgkin's lymphomas
    Kaiser, U
    Trumper, L
    Pfreundschuh, M
    Havemann, K
    INTERNIST, 1997, 38 (02): : 135 - 142
  • [24] Autologous stem cell transplantation in treatment of aggressive non-Hodgkin's lymphoma
    Kluin-Nelemans, HC
    CROATIAN MEDICAL JOURNAL, 2002, 43 (05) : 561 - 564
  • [25] Blinatumomab: a novel therapy for the treatment of non-Hodgkin?s lymphoma
    Bukhari, Ali
    Lee, Seung Tae
    EXPERT REVIEW OF HEMATOLOGY, 2019, 12 (11) : 909 - 918
  • [26] Valoration of a new regime in the treatment of histologically aggressive non-Hodgkin's lymphoma
    Bernabe, R
    Rodriguez, MA
    Bolanos, M
    Borrega, P
    Reina, JJ
    Chaves, M
    Rodriguez, A
    Noguer, M
    Iglesias, L
    Nogueira, JAM
    ANNALS OF ONCOLOGY, 1998, 9 : 112 - 112
  • [27] Treatment of aggressive non-Hodgkin's lymphomas
    Moreno Nogueira, J. A.
    Ruiz Borrego, M.
    Perez Valderrama, B.
    Valero Azbiru, M.
    REVISTA CLINICA ESPANOLA, 2009, 209 (02): : 88 - 92
  • [28] The treatment of Hodgkin's and non-Hodgkin's lymphoma in pregnancy
    Pereg, David
    Koren, Gideon
    Lishner, Michael
    HAEMATOLOGICA, 2007, 92 (09) : 1230 - 1237
  • [29] Randomized trials of transplantation for aggressive non-Hodgkin's lymphoma
    Bierman, PJ
    LEUKEMIA & LYMPHOMA, 1998, 30 : 12 - 12
  • [30] Current Guidelines for the Management of Aggressive Non-Hodgkin’s Lymphoma
    Maurizio Martelli
    Vitaliana De Sanctis
    Giuseppe Avvisati
    Franco Mandelli
    Drugs, 1997, 53 : 957 - 972