A Simple and Economic Synthesis of Propargylamines by CuI-Catalyzed Three-Component Coupling Reaction with Succinic Acid as Additive

被引：28

作者：

Ren, Gerui ^{[1
]}

Zhang, Jinli ^{[1
]}

Duan, Zheng ^{[1
]}

Cui, Mengjun ^{[1
]}

Wu, Yangjie ^{[1
]}

机构：

[1] Zhengzhou Univ, Dept Chem, Henan Key Lab Chem Biol & Organ Chem, Key Lab Appl Chem Henan Univ, Zhengzhou 450052, Peoples R China

来源：

AUSTRALIAN JOURNAL OF CHEMISTRY | 2009年 / 62卷 / 01期

基金：

中国国家自然科学基金;

关键词：

C-H ACTIVATION; EFFICIENT SYNTHESIS; ALDEHYDE; ALKYNE; COPPER; AMINE; SILVER; SALTS; GOLD;

D O I：

10.1071/CH08086

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A practical and efficient method was developed for the synthesis of propargylamines in a one-pot procedure from aldehydes, amines, and alkynes by using CuI as catalyst and succinic acid as additive. By using this protocol, a wide range of propargylamines was obtained in high yields.

引用

页码：75 / 81

页数：7

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