Effects of a novel inverse agonist selective for alpha5 GABAA receptors on spatial memory: comparison with the standard non-selective inverse agonist DMCM

被引：0
|
作者：
Samardzic, J. [1 ]
Savic, M. M. [2 ]
Clayton, T. [3 ]
Rallapalli, S. [3 ]
Obradovic, D. I. [1 ]
Joksimovic, S. M. [4 ]
Sieghart, W. [5 ]
Cook, J. M. [3 ]
机构：
[1] Univ Belgrade, Fac Med, Dept Pharmacol, Belgrade, Serbia
[2] Univ Belgrade, Fac Pharm, Dept Pharmacol, Belgrade, Serbia
[3] Univ Wisconsin, Dept Chem & Biochem, Milwaukee, WI 53201 USA
[4] Med & Med Devices Agcy Serbia, Pharmacol Lab, Belgrade, Serbia
[5] Med Univ Vienna, Ctr Brain Res, Vienna, Austria
来源：
EUROPEAN NEUROPSYCHOPHARMACOLOGY | 2008年 / 18卷
关键词：
D O I：
10.1016/S0924-977X(08)70377-8
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
引用
收藏
页码：S285 / S285
页数：1
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    Szekeres, H. J.
    Szeto, N.
    Scott-Stevens, P.
    Macleod, A. M.
    Braun, M.
    Cato, B.
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