A new turn-on fluorescent probe for selective detection of glutathione and cysteine in living cells

被引：149

作者：

Wei, Mingjie ^{[1
]}

Yin, Peng ^{[1
]}

Shen, Youming ^{[1
]}

Zhang, Lingli ^{[1
]}

Deng, Jianhui ^{[1
]}

Xue, Shanyan ^{[1
]}

Li, Haitao ^{[1
]}

Guo, Bin ^{[1
]}

Zhang, Youyu ^{[1
]}

Yao, Shouzhuo ^{[1
]}

机构：

[1] Hunan Normal Univ, Key Lab Chem Biol & Tradit Chinese Med Res, Minist Educ, Coll Chem & Chem Engn, Changsha 410081, Hunan, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 41期

基金：

中国国家自然科学基金;

关键词：

SENSOR; HOMOCYSTEINE;

D O I：

10.1039/c3cc39045d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A fluorescent probe (N-(4-methyl-2-oxo-2H-chromen-7-yl)-2,4-dinitrobenzenesulfonamide), which exhibits high selectivity to glutathione and cysteine among amino acids including sulphur-containing methionine and metal ions, was synthesized. The experiments demonstrate that the fluorescent probe is a reliable and specific probe for glutathione and cysteine in living cells.

引用

页码：4640 / 4642

页数：3

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