A new turn-on fluorescent probe for selective detection of glutathione and cysteine in living cells

被引:149
|
作者
Wei, Mingjie [1 ]
Yin, Peng [1 ]
Shen, Youming [1 ]
Zhang, Lingli [1 ]
Deng, Jianhui [1 ]
Xue, Shanyan [1 ]
Li, Haitao [1 ]
Guo, Bin [1 ]
Zhang, Youyu [1 ]
Yao, Shouzhuo [1 ]
机构
[1] Hunan Normal Univ, Key Lab Chem Biol & Tradit Chinese Med Res, Minist Educ, Coll Chem & Chem Engn, Changsha 410081, Hunan, Peoples R China
基金
中国国家自然科学基金;
关键词
SENSOR; HOMOCYSTEINE;
D O I
10.1039/c3cc39045d
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A fluorescent probe (N-(4-methyl-2-oxo-2H-chromen-7-yl)-2,4-dinitrobenzenesulfonamide), which exhibits high selectivity to glutathione and cysteine among amino acids including sulphur-containing methionine and metal ions, was synthesized. The experiments demonstrate that the fluorescent probe is a reliable and specific probe for glutathione and cysteine in living cells.
引用
收藏
页码:4640 / 4642
页数:3
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