Synthesis and Characterization of Novel Amino Acid-conjugated Poly(aspartic acid) Derivatives

被引：0
|
作者：
Kim, Seung Il [2 ]
Min, Seok Kee [1 ]
Kim, Ji-Heung [2 ]
机构：
[1] Charmzone Co Ltd, Wonju 220120, Gangwon, South Korea
[2] Sungkyunkwan Univ, Dept Chem Engn, Suwon 440746, Gyonggi, South Korea
来源：
BULLETIN OF THE KOREAN CHEMICAL SOCIETY | 2008年 / 29卷 / 10期
关键词：
Nanoparticle; Poly(aspartic acid); Amphiphilic copolymer; L-Lysine;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Novel poly(aspartic acid) derivatives conjugated with L-lysine moieties and their amphiphilic analogs were synthesized and characterized. The chemical structures of these polymers were confirmed using FT-IR and H-1-NMR spectroscopy. The physicochernical properties of amphiphilic copolymers were characterized using an electrophonctic light scattering spectrophotometer (ELS) and transmission electron microscopy (TEM). These results indicated a stable nanoparticle formation within aqueous media. These polymers have potential applications in the pharmaceutical and cosmetic fields as delivery vehicles for bioactive molecules.
引用
收藏
页码：1887 / 1892
页数：6
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