Thermic effect of food in hypothyroid rats

被引:13
|
作者
Iossa, S [1 ]
Lionetti, L [1 ]
Mollica, MP [1 ]
Barletta, A [1 ]
Liverini, G [1 ]
机构
[1] UNIV NAPLES,DEPT GEN & ENVIRONM PHYSIOL,I-80134 NAPLES,ITALY
关键词
D O I
10.1677/joe.0.1480167
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The regulatory and obligatory components of cephalic and gastrointestinal phases of the thermic effect of food (TEF) were measured in control and hypothyroid rats. A significant decrease (P<0.05) in regulatory and obligatory components of cephalic and gastrointestinal TEF, after either a control or energy-dense meal, was found in hypothyroid rats compared with control rats. Our findings indicate that hypothyroidism is associated with a decreased thermogenic response to food which contributes to the reduced energy expenditure of hypothyroid rats. Our results also suggest that tri-iodothyronine is involved in the regulation of postprandial thermogenesis directly as well as through its influence on beta-adrenergic response and insulin release.
引用
收藏
页码:167 / 174
页数:8
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