Thermic effect of food in hypothyroid rats

被引：13

作者：

Iossa, S ^{[1
]}

Lionetti, L ^{[1
]}

Mollica, MP ^{[1
]}

Barletta, A ^{[1
]}

Liverini, G ^{[1
]}

机构：

[1] UNIV NAPLES,DEPT GEN & ENVIRONM PHYSIOL,I-80134 NAPLES,ITALY

来源：

JOURNAL OF ENDOCRINOLOGY | 1996年 / 148卷 / 01期

关键词：

D O I：

10.1677/joe.0.1480167

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The regulatory and obligatory components of cephalic and gastrointestinal phases of the thermic effect of food (TEF) were measured in control and hypothyroid rats. A significant decrease (P<0.05) in regulatory and obligatory components of cephalic and gastrointestinal TEF, after either a control or energy-dense meal, was found in hypothyroid rats compared with control rats. Our findings indicate that hypothyroidism is associated with a decreased thermogenic response to food which contributes to the reduced energy expenditure of hypothyroid rats. Our results also suggest that tri-iodothyronine is involved in the regulation of postprandial thermogenesis directly as well as through its influence on beta-adrenergic response and insulin release.

引用

页码：167 / 174

页数：8

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