Gonadotropin-releasing hormone antagonists in controlled ovarian stimulation

被引：0

作者：

Diedrich, Klaus ^{[1
]}

Felberbaum, Ricardo ^{[2
]}

Al-Hasani, Safaa ^{[1
]}

机构：

[1] Univ Klinikum Schleswig Holstein, Klin Frauenheilkunde, Ratzeburger Allee 160, D-23538 Lubeck, Germany

[2] Klin Verbund Allgau, Klin Gynakol & Geburtshilfe Kempten & Immenstadt, Kempten, Germany

来源：

GYNAKOLOGE | 2020年 / 53卷 / 08期

关键词：

Ovarian hyperstimulation syndrome; Ovulation induction; Pregnancy rate; Reproductive techniques; assisted; Progesterone; INVITRO FERTILIZATION; CETRORELIX;

D O I：

10.1007/s00129-020-04634-y

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Ovarian stimulation is one of the most important stages in assisted reproduction. The first attempts at stimulation with gonadotropins and gonadotropin-releasing hormone (GnRH) agonists were costly and relatively unsuccessful with many cases of overstimulation. Only the introduction of GnRH antagonists resulted in important progress. The advantages are a shorter duration of treatment and a simplified treatment with less side effects (overstimulation syndrome). In addition, the live birth rate is comparable with that of earlier antagonist protocols. Novel stimulation protocols could be developed with the important possibility to avoid overstimulation (oocyte freezing). In Germany and Europe approximately 70% of the patients are stimulated with the gonadotropins/antagonists protocol.

引用

页码：517 / 521

页数：5

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