Convenient Synthesis of Spirooxindole-Fused Pyrazolopyridine Derivatives

被引：9

作者：

Li, Chunmei ^{[1
]}

Zhang, Furen ^{[1
]}

机构：

[1] Shaoxing Univ, Sch Chem & Chem Engn, Zhejiang Key Lab Alternat Technol Fine Chem Proc, Shaoxing 312000, Zhejiang, Peoples R China

来源：

CHEMISTRYSELECT | 2018年 / 3卷 / 06期

关键词：

Domino reaction; Heterocycles; Pyrazolopyridine; Solid acid; Spirooxindole; NATURAL-PRODUCT SYNTHESIS; ONE-POT; 3-COMPONENT REACTION; EFFICIENT SYNTHESIS; TETRAHYDRO-4H-INDOL-4-ONE DERIVATIVES; CATALYZED CYCLIZATION; CARBONACEOUS MATERIAL; MULTICOMPONENT; NITROOLEFINS; GENERATION;

D O I：

10.1002/slct.201702942

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Concise and efficient three-component domino reaction for the synthesis of spirooxindole fused pyrazolopyridine derivatives has been established. This domino reaction is a green process and can be easily performed in water by using readily available substrates. The present strategy shows attractive characteristics, such as convenient one-pot operation, inexpensive and reusable solid acid catalyst, without time-consuming syntheses and avoiding tedious work-up or purification procedure. A probable mechanism accounting for the reaction is proposed.

引用

页码：1815 / 1819

页数：5

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