Convenient Synthesis of Spirooxindole-Fused Pyrazolopyridine Derivatives

被引：9
|
作者：
Li, Chunmei [1 ]
Zhang, Furen [1 ]
机构：
[1] Shaoxing Univ, Sch Chem & Chem Engn, Zhejiang Key Lab Alternat Technol Fine Chem Proc, Shaoxing 312000, Zhejiang, Peoples R China
来源：
CHEMISTRYSELECT | 2018年 / 3卷 / 06期
关键词：
Domino reaction; Heterocycles; Pyrazolopyridine; Solid acid; Spirooxindole; NATURAL-PRODUCT SYNTHESIS; ONE-POT; 3-COMPONENT REACTION; EFFICIENT SYNTHESIS; TETRAHYDRO-4H-INDOL-4-ONE DERIVATIVES; CATALYZED CYCLIZATION; CARBONACEOUS MATERIAL; MULTICOMPONENT; NITROOLEFINS; GENERATION;
D O I：
10.1002/slct.201702942
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Concise and efficient three-component domino reaction for the synthesis of spirooxindole fused pyrazolopyridine derivatives has been established. This domino reaction is a green process and can be easily performed in water by using readily available substrates. The present strategy shows attractive characteristics, such as convenient one-pot operation, inexpensive and reusable solid acid catalyst, without time-consuming syntheses and avoiding tedious work-up or purification procedure. A probable mechanism accounting for the reaction is proposed.
引用
收藏
页码：1815 / 1819
页数：5
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