Sonogashira cross-coupling reaction of 3-iodoindazoles with various terminal alkynes: a mild and flexible strategy to design 2-aza tryptamines

被引：46
|
作者：
Arnautu, A
Collot, V
Ros, JC
Alayrac, C
Witulski, B
Rault, S
机构：
[1] Ctr Etudes Rech Medicament Normandie, UFR Sci Pharmaceut, F-14032 Caen, France
[2] Univ Kaiserslautern, Fachbereich Chem, D-67663 Kaiserslautern, Germany
来源：
TETRAHEDRON LETTERS | 2002年 / 43卷 / 15期
关键词：
D O I：
10.1016/S0040-4039(02)00393-3
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
This paper describes a Sonogashira-type cross-coupling reaction of 3-iodoindazoles various terminal alkynes as a general route to 3-alkynylindazoles. The Coupling reaction is illustrated by the preparation of ne indazolylpropiolic or propargylic derivatives. Scope and limitation of the method are outlined. (C) 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：2695 / 2697
页数：3
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