EFFECT OF NATURAL POLYPHENOLS ON EPIGENETIC MECHANISMS OF GENE EXPRESSION

被引：0
|
作者：
Lewandowska, Patrycja [1 ]
Wozniak, Katarzyna [1 ]
机构：
[1] Uniwersytet Lodzki, Wydzial Biol & Ochrony Srodowiska, Katedra Genet Mol, Ul Pomorska 141-143, PL-90236 Lodz, Poland
来源：
POSTEPY BIOLOGII KOMORKI | 2017年 / 44卷 / 02期
关键词：
epigenetics; resveratrol; curcumin; genistein; BREAST-CANCER CELLS; TUMOR-SUPPRESSOR GENES; PROSTATE-CANCER; DNA METHYLATION; RESVERATROL SUPPLEMENTATION; HISTONE MODIFICATIONS; PROMOTER METHYLATION; SIRT1; ACTIVATION; IN-VITRO; RAR-BETA;
D O I：
暂无
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
In recent years, interest in nutrigenomics which studies the relationship between human diet and the expression of its genes has increased. The article presents data on the influence of selected dietary components resveratrol, genistein and curcumin on epigenetic mechanisms of gene expression control, such as DNA methylation and histone modifications methylation, acetylation and deacetylation. The ability of bioactive food components to epigenetic modulation of gene expression can be a key element in the prevention and treatment of diseases, such as type 2 diabetes, obesity, hypertension or cancer.
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页码：213 / 225
页数：25
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