SYNTHESIS OF 3-[2-(SUBSTITUTED SULFONYL)-1H-IMIDAZOL-YL] CHROMEN-2-ONE DERIVATIVES

被引:0
|
作者
Guravaiah, Nalajam [1 ]
Rao, Vedula Rajeswar [1 ]
机构
[1] Natl Inst Technol, Dept Chem, Warangal 506021, Andhra Pradesh, India
关键词
D O I
暂无
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Reaction of 3-(2-Mercapto-1H-imidazol-4-yl)chromen-2-one (1) with various alkyl/aryl/phenacyl halides in a mixture of anhydrous ethanol and dimethyl formamide gave the corresponding 3-(2-substituted sulfanyl-1H-imidazol-4-yl)chromen-2-ones (2). These on further reaction with hydrogen peroxide in acetic acid resulted in the formation of corresponding sulfones(3) in good yields the structure of the synthesized compounds were established from evidences like IR,NMR and mass spectral data.
引用
收藏
页码:367 / 374
页数:8
相关论文
共 50 条
  • [31] Synthesis and Antimicrobial Activity of 2-(Pyridine-3-yl)-4H-chromen-4-one Derivatives
    Chate, Asha V.
    Ghotekar, Dattatraya S.
    Bhagat, Sunil S.
    Gill, Charansingh H.
    [J]. JOURNAL OF HETEROCYCLIC CHEMISTRY, 2013, 50 (01) : 149 - 154
  • [32] Synthesis of 3-(4, 5-dihydro-1-phenyl-5-substituted phenyl-1H-pyrazol-3-yl)-2H-chromen-2-one derivatives and evaluation of their anticancer activity
    Kumar, Nitin
    Bhatnagar, Ankita
    Dudhe, Rupesh
    [J]. ARABIAN JOURNAL OF CHEMISTRY, 2017, 10 : S2443 - S2452
  • [33] An Efficient Solid-Phase Green Synthesis of Chromen-2-one Derivatives
    Tasqeeruddin, S.
    Al-Arifi, Abdullah S.
    Dubey, P. K.
    [J]. ASIAN JOURNAL OF CHEMISTRY, 2013, 25 (12) : 6885 - 6887
  • [34] Synthesis, antimycobacterial activity, and acid dissociation constants of polyfunctionalized 3-[2-(pyrrolidin-1-yl)thiazole-5-carbonyl]-2H-chromen-2-one derivatives
    Yahya Nural
    [J]. Monatshefte für Chemie - Chemical Monthly, 2018, 149 : 1905 - 1918
  • [35] Synthesis, antimycobacterial activity, and acid dissociation constants of polyfunctionalized 3-[2-(pyrrolidin-1-yl)thiazole-5-carbonyl]-2H-chromen-2-one derivatives
    Nural, Yahya
    [J]. MONATSHEFTE FUR CHEMIE, 2018, 149 (10): : 1905 - 1918
  • [36] MICROWAVE ASSISTED SYNTHESIS OF 3-[2-(1H-BENZIMIDAZOL-2-YL-SULFANYL)-ACETYL]-CHROMEN-2-ONES
    Dubey, P. K.
    Kumar, N. D. Mahesh
    Chaitanya, M. V. S. R. K.
    Tasqeeruddin, Syed
    [J]. INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2010, 19 (03) : 285 - 286
  • [37] A two-component protocol for synthesis of 3-(2-(substituted phenylamino)thiazol-4-yl)-2H-chromen-2-ones
    Saeed, Aamer
    Arif, Mubeen
    Irfan, Madiha
    Bolte, Michael
    [J]. TURKISH JOURNAL OF CHEMISTRY, 2013, 37 (03) : 383 - 393
  • [38] Green synthesis of chromen-2-one derivatives catalysed by L-proline
    Shi, Chunling
    Shi, Da-Qing
    [J]. JOURNAL OF CHEMICAL RESEARCH, 2011, (10) : 585 - 586
  • [39] SYNTHESIS OF NEW 3-(1-ARYL-2-THIOXO-3,4-DIHYDRO-2H-IMIDAZOL-4-YL) CHROMEN-2-ONES
    Soman, Shubhangi S.
    Thaker, Tirth H.
    [J]. INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2009, 19 (01) : 55 - 58
  • [40] 3-{2-[2-(3-Hydroxybenzylidene)hydrazin-1-yl]-1,3-thiazol-4-yl}-2H-chromen-2-onehemihydrate
    Arshad, Afsheen
    Osman, Hasnah
    Chan, Kit Lam
    Goh, Jia Hao
    Fun, Hoong-Kun
    [J]. ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 : O1498 - U2161