Telomeres: has cancer's Achilles' heel been exposed?

被引：14
|
作者：
Zumstein, LA [1 ]
Lundblad, V
机构：
[1] Introgen Therapeut Inc, Houston, TX 77030 USA
[2] Baylor Coll Med, Dept Mol & Human Genet, Houston, TX 77030 USA
来源：
NATURE MEDICINE | 1999年 / 5卷 / 10期
关键词：
D O I：
10.1038/13451
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Telomerase allows cells to grow indefinitely, and is expressed in the majority of human cancers. New data suggest, however, that telomere maintenance might be a stumbling block on the path to immortalization and that inhibition of telomere replication can attenuate human cancer cell growth (pages 1164–1170) .
引用
收藏
页码：1129 / 1130
页数：2
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