Telomeres: has cancer's Achilles' heel been exposed?

被引：0
|
作者：
Louis A Zumstein
Victoria Lundblad
机构：
[1] Introgen Therapeutics,Department of Molecular and Human Genetics
[2] Inc,undefined
[3] Baylor College of Medicine,undefined
来源：
Nature Medicine | 1999年 / 5卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Telomerase allows cells to grow indefinitely, and is expressed in the majority of human cancers. New data suggest, however, that telomere maintenance might be a stumbling block on the path to immortalization and that inhibition of telomere replication can attenuate human cancer cell growth (pages 1164–1170) .
引用
收藏
页码：1129 / 1130
页数：1
相关论文
共 50 条
  • [1] Telomeres: has cancer's Achilles' heel been exposed?
    Zumstein, LA
    Lundblad, V
    [J]. NATURE MEDICINE, 1999, 5 (10) : 1129 - 1130
  • [2] HER2/neu overexpression: has the Achilles' heel of uterine serous papillary carcinoma been exposed?
    Santin, AD
    [J]. GYNECOLOGIC ONCOLOGY, 2003, 88 (03) : 263 - 265
  • [3] Breast cancer has a new metabolic Achilles’ heel
    Tatiana Alfonso-Pérez
    Gabriel Baonza
    Fernando Martin-Belmonte
    [J]. Nature Metabolism, 2021, 3 : 590 - 592
  • [4] Breast cancer has a new metabolic Achilles' heel
    Alfonso-Perez, Tatiana
    Baonza, Gabriel
    Martin-Belmonte, Fernando
    [J]. NATURE METABOLISM, 2021, 3 (05) : 590 - 592
  • [5] The pyrimidinosome is cancer’s Achilles’ heel
    Matthew Dodson
    Donna D. Zhang
    [J]. Nature Cell Biology, 2023, 25 : 798 - 799
  • [6] Targeting Cancer's Achilles Heel
    Brower, Vicki
    [J]. SCIENTIST, 2018, 32 (04): : 62 - 65
  • [7] Finding cancer's Achilles' heel
    Owens, J
    [J]. NATURE REVIEWS DRUG DISCOVERY, 2006, 5 (05) : 374A - 374A
  • [8] The pyrimidinosome is cancer's Achilles' heel
    Dodson, Matthew
    Zhang, Donna D.
    [J]. NATURE CELL BIOLOGY, 2023, 25 (06) : 798 - 799
  • [9] Cancer's new Achilles' heel?
    Owen, Gareth I.
    [J]. ONCOTARGET, 2017, 8 (34) : 55774 - 55775
  • [10] Finding cancer's Achilles' heel
    Joanna Owens
    [J]. Nature Reviews Drug Discovery, 2006, 5 : 374 - 374
12345