α-GLUCOSIDASE INHIBITORY CONSTITUENTS FROM Trichosanthis Radix

被引：0
|
作者：
Chen, Xue-Lin [1 ,2 ]
Zhang, Kun [1 ]
Ni, Ji-Yan [1 ,2 ]
Zhao, Xia [1 ]
Zhang, Yu-Mei [1 ,2 ]
机构：
[1] Chinese Acad Sci, Xishuangbanna Trop Bot Garden, Key Lab Trop Plant Resources & Sustainable Use, Kunming 650223, Yunnan, Peoples R China
[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
来源：
CHEMISTRY OF NATURAL COMPOUNDS | 2022年 / 58卷 / 05期
关键词：
Trichosanthis Radix; hypoglycemic activities; alpha-glucosidase; CHEMICAL-CONSTITUENTS;
D O I：
10.1007/s10600-022-03800-z
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
One new compound, beta-D-apiofuranosyl-(1 -> 6)-1-ethyl-O-beta-D-glucopyranoside (1), and 11 known compounds were isolated from Trichosanthis Radix. Their structures were mainly elucidated by NMR and MS spectra. All the isolated compounds were tested for their inhibitory activities against alpha-glucosidase, and compound 11 exhibited potential inhibitory activity with an IC50 value of 36.41 +/- 0.54 mu M.
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页码：796 / 798
页数：3
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