Organofluorine Chemistry: Deoxyfluorination Reagents for C-F Bond Synthesis

被引：0
|
作者：
Al-Maharik, Nawaf [1 ]
O'Hagan, David [1 ]
机构：
[1] Univ St Andrews, EastChem Sch Chem, St Andrews KY16 9ST, Fife, Scotland
来源：
ALDRICHIMICA ACTA | 2011年 / 44卷 / 03期
关键词：
fluoroalkanes; C-F bond; organofluorine chemistry; fluorination reagents; deoxyfluorination; SPECTRUM DEOXOFLUORINATING AGENT; DIETHYLAMINE ADDUCT PPDA; BIS(2-METHOXYETHYL)AMINOSULFUR TRIFLUORIDE; DIALKYLAMINOSULFUR TRIFLUORIDES; ENANTIOSELECTIVE SYNTHESIS; BIOLOGICAL EVALUATION; EFFICIENT SYNTHESIS; ALLYLIC ALCOHOLS; GABA BINDING; FLUORINATION;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The influence of the C-F bond on the conformation of organic molecules is outlined. Strategies for incorporating the C-F bond into molecular frameworks by deoxyfluorination reactions are summarized with a particular focus on recent and emerging fluorination reagents. The syntheses of individual stereoisomers of straight-chain alkanes carrying up to six consecutive C-F bonds is presented to illustrate the power of the deoxyfluorination approach in controlling the introduction of the C-F bond at a stereogenic center.
引用
收藏
页码：65 / 75
页数：11
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