PyPanda: a Python']Python package for gene regulatory network reconstruction

被引:8
|
作者
van IJzendoorn, David G. P. [1 ]
Glass, Kimberly [2 ]
Quackenbush, John [3 ,4 ,5 ]
Kuijjer, Marieke L. [3 ,4 ]
机构
[1] Leiden Univ, Dept Pathol, Med Ctr, NL-2300 RC Leiden, Netherlands
[2] Harvard Med Sch, Brigham & Womens Hosp, Channing Div Network Med, Dept Med, Boston, MA 02215 USA
[3] Dana Farber Canc Inst, Dept Biostat & Computat Biol, Boston, MA 02215 USA
[4] Harvard TH Chan Sch Publ Hlth, Dept Biostat, Boston, MA 02215 USA
[5] Dana Farber Canc Inst, Dept Canc Biol, Boston, MA 02215 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1093/bioinformatics/btw422
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
PANDA (Passing Attributes between Networks for Data Assimilation) is a gene regulatory network inference method that uses message-passing to integrate multiple sources of 'omics data. PANDA was originally coded in C++. In this application note we describe PyPanda, the Python version of PANDA. PyPanda runs considerably faster than the C++version and includes additional features for network analysis. Availability and implementation: The open source PyPanda Python package is freely available at http://github.com/davidvi/pypanda. Contact: mkuijjer@jimmy.harvard.edu or d.g.p.van_ijzendoorn@lumc.nl
引用
收藏
页码:3363 / 3365
页数:3
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