Plasma levels of interleukin-38 in healthy aging and in type 2 diabetes

被引：16
|
作者：
Gurau, Felicia [1 ]
Silvestrini, Andrea [1 ]
Matacchione, Giulia [1 ]
Fazioli, Francesca [1 ]
Bonfigli, Anna Rita [2 ]
Olivieri, Fabiola [1 ,3 ]
Sabbatinelli, Jacopo [1 ]
机构：
[1] Univ Politecn Marche, DISCLIMO, Dept Clin & Mol Sci, Via Tronto 10-A, Ancona, Italy
[2] IRCCS INRCA, Sci Direct, Ancona, Italy
[3] IRCCS INRCA, Ctr Clin Pathol & Innovat Therapy, Ancona, Italy
来源：
DIABETES RESEARCH AND CLINICAL PRACTICE | 2021年 / 171卷
关键词：
Type; 2; diabetes; Interleukin-38; Inflammation; Age-related diseases; Aging; AGE; DISEASE; IL-38;
D O I：
10.1016/j.diabres.2020.108585
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Plasma levels of interleukin (IL)-38 were evaluated in patients with type 2 diabetes (T2DM) and healthy controls. Plasma IL-38 was higher in T2DM patients and positively related to waist/hip ratio, HbA1c, uric acid, liver function tests, triglycerides and total proteins. Patients suffering from diabetic nephropathy had the highest IL-38 levels. (C) 2020 Elsevier B.V. All rights reserved.
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页数：6
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