Plasma levels of interleukin-38 in healthy aging and in type 2 diabetes

被引：16

作者：

Gurau, Felicia ^{[1
]}

Silvestrini, Andrea ^{[1
]}

Matacchione, Giulia ^{[1
]}

Fazioli, Francesca ^{[1
]}

Bonfigli, Anna Rita ^{[2
]}

Olivieri, Fabiola ^{[1
,3
]}

Sabbatinelli, Jacopo ^{[1
]}

机构：

[1] Univ Politecn Marche, DISCLIMO, Dept Clin & Mol Sci, Via Tronto 10-A, Ancona, Italy

[2] IRCCS INRCA, Sci Direct, Ancona, Italy

[3] IRCCS INRCA, Ctr Clin Pathol & Innovat Therapy, Ancona, Italy

来源：

DIABETES RESEARCH AND CLINICAL PRACTICE | 2021年 / 171卷

关键词：

Type; 2; diabetes; Interleukin-38; Inflammation; Age-related diseases; Aging; AGE; DISEASE; IL-38;

D O I：

10.1016/j.diabres.2020.108585

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Plasma levels of interleukin (IL)-38 were evaluated in patients with type 2 diabetes (T2DM) and healthy controls. Plasma IL-38 was higher in T2DM patients and positively related to waist/hip ratio, HbA1c, uric acid, liver function tests, triglycerides and total proteins. Patients suffering from diabetic nephropathy had the highest IL-38 levels. (C) 2020 Elsevier B.V. All rights reserved.

引用

页数：6

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