(3+2) Cycloadditions of Thiouronium Ylides: A Room-Temperature, One-Pot Approach to Dihydrothiophenes

被引:10
|
作者
Neuhaus, James D. [1 ]
Angyal, Peter [1 ]
Oost, Rik [1 ]
Maulide, Nuno [1 ]
机构
[1] Univ Vienna, Inst Organ Chem, Wahringer Str 38, A-1090 Vienna, Austria
来源
JOURNAL OF ORGANIC CHEMISTRY | 2018年 / 83卷 / 04期
关键词
THIOCARBONYL YLIDES; CONDENSED CHROMONES; CYCLOPROPANATION; DERIVATIVES; MOLECULES; THIOBENZOPHENONE; PHOTOGENERATION; REARRANGEMENT; DIAZOMETHANE; CYCLIZATION;
D O I
10.1021/acs.joc.7b03255
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A room-temperature (3+2) cycloaddition sequence for the synthesis of highly substituted dihydrothiophene derivatives has been developed. By utilizing structurally unique thiocarbonyl ylides, the reactivity of these traditionally high-energy intermediates can be modulated, enabling a synthetically useful transformation to proceed under mild conditions.
引用
收藏
页码:2479 / 2485
页数:7
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