Molecular Understanding of the Binding of Macrolide Antibiotics to the Ribosome using Site-Identification via Ligand Competitive Saturation

被引：0
|
作者：
Small, Meagan C. [1 ]
Lakkaraju, Sirish Kaushik [1 ]
Raman, E. Prabhu [1 ]
Andrade, Rodrigo B. [2 ]
MacKerell, Alexander D., Jr. [1 ]
机构：
[1] Univ Maryland, Dept Pharmaceut Sci, Baltimore, MD 21201 USA
[2] Temple Univ, Dept Chem, Philadelphia, PA 19122 USA
来源：
BIOPHYSICAL JOURNAL | 2015年 / 108卷 / 02期
关键词：
D O I：
10.1016/j.bpj.2014.11.2566
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
2367-Pos
引用
收藏
页码：469A / 469A
页数：1
相关论文
共 50 条
  • [31] Binding site of macrolide antibiotics on the ribosome: New resistance mutation identifies a specific interaction of ketolides with rRNA
    Garza-Ramos, G
    Xiong, LQ
    Zhong, P
    Mankin, A
    JOURNAL OF BACTERIOLOGY, 2001, 183 (23) : 6898 - 6907
  • [32] Comparison of Functional Group Affinity Patterns from the Additive Versus Drude Polarizable Force Fields from the Site-Identification by Ligand Competitive Saturation (SILCS) Approach
    Goel, Himanshu
    Sun, Delin Sun
    Yu, Wenbo
    MacKerell, Alexander D.
    BIOPHYSICAL JOURNAL, 2019, 116 (03) : 142A - 142A
  • [33] Identification of ligand binding site on RXRγ using molecular docking and dynamics methods
    Peng Zhao
    Qing-hua Liao
    Cheng-Feng Ren
    Jing Wei
    Journal of Molecular Modeling, 2011, 17 : 1259 - 1265
  • [34] Identification of ligand binding site on RXRγ using molecular docking and dynamics methods
    Zhao, Peng
    Liao, Qing-hua
    Ren, Cheng-Feng
    Wei, Jing
    JOURNAL OF MOLECULAR MODELING, 2011, 17 (06) : 1259 - 1265
  • [35] Inclusion of Multiple Fragment Types in the Site Identification by Ligand Competitive Saturation (SILCS) Approach
    Raman, E. Prabhu
    Yu, Wenbo
    Lakkaraju, Sirish K.
    MacKerell, Alexander D., Jr.
    JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2013, 53 (12) : 3384 - 3398
  • [36] hERG Blockade Prediction by Combining Site Identification by Ligand Competitive Saturation and Physicochemical Properties
    Goel, Himanshu
    Yu, Wenbo
    MacKerell, Alexander D., Jr.
    CHEMISTRY-SWITZERLAND, 2022, 4 (03): : 630 - 646
  • [37] Protein Affinity Pattern Calculations using Protein-Fragment Site Identification by Ligand Competitive Saturation (SILCS)
    Raman, E. Prabhu
    Yu, Wenbo
    MacKerell, Alexander D., Jr.
    BIOPHYSICAL JOURNAL, 2011, 100 (03) : 526 - 526
  • [38] Grand canonical solute sampling in combination with the site identification by ligand competitive saturation (SILCS) ligand design methodology
    Lakkaraju, Sirish
    Raman, E.
    Yu, Wenbo
    Mackerell, Alexander
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 251
  • [39] Ligand Binding Site Identification by Higher Dimension Molecular Dynamics
    Yatawara, Achani K.
    Hodoscek, Milan
    Mierke, Dale F.
    JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2013, 53 (03) : 674 - 680
  • [40] Functional Group Distributions, Partition Coefficients, and Resistance Factors in Lipid Bilayers Using Site Identification by Ligand Competitive Saturation
    Lind, Christoffer
    Pandey, Poonam
    Pastor, Richard W.
    MacKerell, Alexander D., Jr.
    JOURNAL OF CHEMICAL THEORY AND COMPUTATION, 2021, 17 (05) : 3188 - 3202
12345