Highly Selective β-Hydride Elimination in Pd-Catalyzed Decarboxylative Heck-Type Reaction

被引：60
|
作者：
Huang, Liangbin [1 ]
Qi, Ji [1 ]
Wu, Xia [1 ]
Huang, Kefan [1 ]
Jiang, Huanfeng [1 ]
机构：
[1] S China Univ Technol, Sch Chem & Chem Engn, Guangzhou 510640, Peoples R China
来源：
ORGANIC LETTERS | 2013年 / 15卷 / 10期
基金：
中国国家自然科学基金;
关键词：
C-H OLEFINATION; ELECTRON-DEFICIENT ARENES; CROSS-COUPLING REACTION; CARBOXYLIC-ACIDS; BOND FORMATION; PD(II)-CATALYZED OLEFINATION; STEREOSELECTIVE-SYNTHESIS; SUBSTITUTED NAPHTHALENES; AEROBIC DEHYDROGENATION; THEORETICAL-ANALYSIS;
D O I：
10.1021/ol400818v
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A variety of beta-aryl ketones and aldehydes were facilely synthesized via a Pd(II)/Ag2CO3-mediated decarboxylative Heck type reaction between readily available benzoic acid derivatives and allylic alcohols under mild conditions. The control experiments indicated that this transformation may proceed via a hydrogen migration process.
引用
收藏
页码：2330 / 2333
页数：4
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