Hydrotrope: green and rapid approach for the catalyst-free synthesis of pyrazole derivatives

被引:21
|
作者
Barge, Madhuri [1 ]
Kamble, Santosh [1 ]
Kumbhar, Arjun [1 ]
Rashinkar, Gajanan [1 ]
Salunkhe, Rajashri [1 ]
机构
[1] Shivaji Univ, Dept Chem, Kolhapur 416004, Maharashtra, India
来源
MONATSHEFTE FUR CHEMIE | 2013年 / 144卷 / 08期
关键词
Green chemistry; Surfactants; Hydrotrope; Water; Pyrazoles; EFFICIENT; INHIBITORS; INTENSIFICATION; DIAZEPINES; ESTERS; WATER;
D O I
10.1007/s00706-013-0944-4
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
An efficient synthesis of pyrazole derivatives by condensation of 1,3-diketone and hydrazines/hydrazides has been achieved in aqueous hydrotropic solution under catalyst-free conditions within a very short time. The present protocol is beneficial as it includes mild reaction conditions, shorter reaction times, use of universal solvent water, which avoids volatile organic solvents, high yields of products, and being environmentally friendly.
引用
收藏
页码:1213 / 1218
页数:6
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