Role of therapeutic vaccines in the control of HIV-1

被引：9

作者：

Kinloch-de Loes, S

机构：

[1] UCL Royal Free & Univ Coll Med Sch, Royal Free Ctr HIV Med, Dept HIV Thorac Med, London NW3 2PF, England

[2] UCL Royal Free & Univ Coll Med Sch, Royal Free Ctr HIV Med, Dept Med, London NW3 2PF, England

[3] UCL Royal Free & Univ Coll Med Sch, Royal Free Ctr HIV Med, Dept Immunol & Mol Pathol, London NW3 2PF, England

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 2004年 / 53卷 / 04期

关键词：

immune control; immune-based therapies; HIV; highly active antiretroviral therapy;

D O I：

10.1093/jac/dkh132

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The recent success of highly active antiretroviral therapy (HAART) has altered the prognosis of patients living with HIV-1 infection. However, there are still many challenges to be addressed if we want to develop long-term therapeutic strategies for patients, in both the Western world and resource-poor countries. In this review, the potential role for HIV-1 therapeutic vaccines in the era of HAART will be discussed in the light of the present efforts at developing immune-based therapies to complement antiviral treatment and minimize the duration of exposure to antiviral drugs.

引用

页码：562 / 566

页数：5

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