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Role of therapeutic vaccines in the control of HIV-1
被引:9
|作者:
Kinloch-de Loes, S
机构:
[1] UCL Royal Free & Univ Coll Med Sch, Royal Free Ctr HIV Med, Dept HIV Thorac Med, London NW3 2PF, England
[2] UCL Royal Free & Univ Coll Med Sch, Royal Free Ctr HIV Med, Dept Med, London NW3 2PF, England
[3] UCL Royal Free & Univ Coll Med Sch, Royal Free Ctr HIV Med, Dept Immunol & Mol Pathol, London NW3 2PF, England
关键词:
immune control;
immune-based therapies;
HIV;
highly active antiretroviral therapy;
D O I:
10.1093/jac/dkh132
中图分类号:
R51 [传染病];
学科分类号:
100401 ;
摘要:
The recent success of highly active antiretroviral therapy (HAART) has altered the prognosis of patients living with HIV-1 infection. However, there are still many challenges to be addressed if we want to develop long-term therapeutic strategies for patients, in both the Western world and resource-poor countries. In this review, the potential role for HIV-1 therapeutic vaccines in the era of HAART will be discussed in the light of the present efforts at developing immune-based therapies to complement antiviral treatment and minimize the duration of exposure to antiviral drugs.
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页码:562 / 566
页数:5
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