Design, synthesis and biological activity of novel quinazolinone-based Caspase 3 inhibitors

被引：0
|
作者：
Greenfield, A
Grosanu, C
Tawa, GJ
Childers, WE
Harrison, BL
Magolda, RL
Robichaud, AJ
Aulabaugh, A
Chan, H
Cowling, R
Fennel, M
Huang, XY
Hum, WT
Kapoor, B
Ling, HP
Wood, A
机构：
[1] Wyeth Ayerst Res, Chem & Screening Sci, Princeton, NJ 08543 USA
[2] Wyeth Ayerst Res, Neurosci, Princeton, NJ 08543 USA
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2005年 / 230卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
318-MEDI
引用
收藏
页码：U2684 / U2684
页数：1
相关论文
共 50 条
  • [21] Characterization, biological evaluation and molecular docking of a synthesised quinazolinone-based derivative
    Alossaimi, Manal A.
    Riadi, Yassine
    Geesi, Mohammed H.
    Anouar, El Hassane
    Aldhafiri, Madhwi K.
    Alanazi, Asma I.
    Dehbi, Oussama
    Ibnouf, Elmutasim O.
    Azzallou, Rachid
    JOURNAL OF MOLECULAR STRUCTURE, 2022, 1266
  • [22] Design, Synthesis & Biological Evaluation of Some Novel Quinazolinone Scaffolds
    Modh, Rahul P.
    Patel, Amit C.
    Chikhalia, Kishor H.
    MEDICINAL CHEMISTRY, 2012, 8 (02) : 182 - 192
  • [23] Design, synthesis, and anticonvulsant activity of novel quinazolinone analogues
    Gawad, Nagwa M. Abdel
    Georgey, Hanan Hanna
    Youssef, Riham M.
    El Sayed, Nehad A.
    MEDICINAL CHEMISTRY RESEARCH, 2011, 20 (08) : 1280 - 1286
  • [24] Synthesis of Some Novel Quinazolinone Derivatives with Anticipated Biological Activity
    Marzouk, Magda I.
    Shaker, Soheir A.
    Farghaly, Thoraya A.
    El-Hashash, Maher A.
    Hussein, Shadia M.
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2017, 54 (06) : 3331 - 3341
  • [25] Design, synthesis, and anticonvulsant activity of novel quinazolinone analogues
    Nagwa M. Abdel Gawad
    Hanan Hanna Georgey
    Riham M. Youssef
    Nehad A. El Sayed
    Medicinal Chemistry Research, 2011, 20 : 1280 - 1286
  • [26] Synthesis and biological evaluation of novel oxalamido derivatives as caspase-3 inhibitors
    Sengupta, Saumitra
    Rao, G. Venkateshwar
    Dubey, P. K.
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2011, 50 (07): : 901 - 905
  • [27] Design, synthesis, biological evaluation, and molecular docking of novel quinazolinone EGFR inhibitors as targeted anticancer agents
    Nofal, Zinab M.
    Amin, Kamelia M.
    Mohamed, Hanaa S.
    El-Kerdawy, Ahmed M.
    Aly, Magdy S.
    Habib, Basma S.
    Sarhan, Alaadin E.
    SYNTHETIC COMMUNICATIONS, 2022, 52 (18) : 1805 - 1824
  • [28] New quinazolinone-based Mannich bases: Synthesis and in vitro cytotoxic evaluation
    Minh, Nguyen Van
    Thao, Nguyen Thi Phuong
    Linh, Nguyen Pham Duy
    Vu, Tran Khac
    INDIAN JOURNAL OF CHEMISTRY, 2023, 62 (03): : 244 - 250
  • [29] Quinazolinone-based rhodanine-3-acetic acids as potent aldose reductase inhibitors: Synthesis, functional evaluation and molecular modeling study
    El-sayed, Sherihan
    Metwally, Kamel
    El-Shanawani, Abdalla A.
    Abdel-Aziz, Lobna M.
    El-Rashedy, Ahmed A.
    Soliman, Mahmoud E. S.
    Quattrini, Luca
    Coviello, Vito
    la Motta, Concettina
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 27 (20) : 4760 - 4764
  • [30] Quinazolinone-based benzenesulfonamides with low toxicity and high affinity as monoamine oxidase-A inhibitors: Synthesis, biological evaluation and induced-fit docking studies
    Yamali, Cem
    Gul, Halise Inci
    Sakarya, Mehtap Tugrak
    Saglik, Begum Nurpelin
    Ece, Abdulilah
    Demirel, Goksun
    Nenni, Merve
    Levent, Serkan
    Oner, Ahmet Cihat
    BIOORGANIC CHEMISTRY, 2022, 124
12345