Simple and convenient synthesis of (±)-bakuchiol

被引:10
|
作者
Chen, Hongli [1 ]
Li, Yuanchao [1 ]
机构
[1] Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China
关键词
(+/-)-bakuchiol; citral; 1,4-addition; Grignard reagent;
D O I
10.2174/157017808785740499
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A simple and convenient synthesis of (+/-)-bakuchiol has been developed. The key intermediate was obtained in only one step from the easily available starting material, citral, by an 1,4-addition procedure. (+/-)-Bakuchiol was finally produced in 4 steps to give 50% overall yield.
引用
收藏
页码:467 / 469
页数:3
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