Greener synthesis of ZnO and Ag-ZnO nanoparticles using Silybum marianum for diverse biomedical applications

被引：122
|
作者：
Hameed, Safia [1 ]
Khalil, Ali T. [2 ,3 ,4 ]
Ali, Muhammad [1 ]
Numan, Muhammad [1 ]
Khamlich, Saleh [3 ,4 ]
Shinwari, Zabta K. [2 ,5 ]
Maaza, Malik [2 ,4 ]
机构：
[1] Quaid I Azam Univ, Dept Biotechnol, Islamabad, Pakistan
[2] Qarshi Univ, Dept Eastern Med & Surg, Lahore, Pakistan
[3] Univ South Africa, UNESCO UNISA Africa Chair Nanosci & Nanotechnol, Coll Grad Studies, Pretoria, South Africa
[4] IThemba LABS, Nanosci African Network NANOAFNET, Mat Res Dept, Cape Town, South Africa
[5] Pakistan Acad Sci, Islamabad, Pakistan
来源：
NANOMEDICINE | 2019年 / 14卷 / 06期
基金：
新加坡国家研究基金会;
关键词：
Ag-ZnO; antileishmanial; antimicrobial; antioxidant; enzyme inhibition; nanocomposite; nanoparticles; nanoscosmaceutical; Silybum marianum; ZnO; ZINC-OXIDE NANOPARTICLES; LEAF EXTRACT; IN-VITRO; ANTIBACTERIAL ACTIVITY; PHYTOCHEMICAL ANALYSIS; METHANOLIC EXTRACT; CANCER-CELLS; BIOSYNTHESIS; ANTIOXIDANT; NANOSTRUCTURES;
D O I：
10.2217/nnm-2018-0279
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Aim: To investigate the physical and biological properties of Silybum marianum inspired ZnO nanoparticles (NPs), Ag-ZnO heterostructures. Experiment: Nanoparticles were characterized using ultraviolet-visible and infrared spectroscopy, x-ray diffraction, high resolution electron microscopy, zeta potential and thermo-gravimetric analysis etc. Results: Ag-ZnO-NPs indicated slightly higher antimicrobial potential then ZnO-NPs. Good antileishmanial (IC50 = 246 mu g/ml for Ag-ZnO; 341 mu g/ml for ZnO) and antioxidant potential while moderate enzyme inhibition is reported. 2, 2-Diphenyl 1-picrylhydrazyl radical scavenging of Ag-ZnO was higher relative to ZnO-NPs. Nanocosmaceutical formulation of nanoparticles indicated stable antimicrobial performance. Conclusion: Biosynthesized nanoparticles indicated interesting biological properties and should be subjected to further research to establish their pharmacological relevance.
引用
收藏
页码：655 / 673
页数：19
相关论文
共 50 条
  • [41] Synthesis, characterization, antibacterial and antifungal properties of ZnO and Ag doped ZnO nanoparticles
    Malaeru, T.
    Morari, C.
    Nicula, N. O.
    Sbarcea, B. G.
    Marinescu, V.
    Cucos, A.
    Moanta, A.
    Georgescu, G.
    Banciu, C. A.
    JOURNAL OF OPTOELECTRONICS AND ADVANCED MATERIALS, 2024, 26 (1-2): : 64 - 73
  • [42] Synthesis of Core/Shell (ZnO/Ag) Nanoparticles Using Calotropis gigantea and Their Applications in Photocatalytic and Antibacterial Studies
    Kumar, Rajith C. R.
    Betageri, Virupaxappa S.
    Nagaraju, G.
    Pujar, G. H.
    Onkarappa, H. S.
    Latha, M. S.
    JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS, 2020, 30 (09) : 3410 - 3417
  • [43] Synthesis of Core/Shell (ZnO/Ag) Nanoparticles Using Calotropis gigantea and Their Applications in Photocatalytic and Antibacterial Studies
    C. R. Rajith Kumar
    Virupaxappa S. Betageri
    G. Nagaraju
    G. H. Pujar
    H. S. Onkarappa
    M. S. Latha
    Journal of Inorganic and Organometallic Polymers and Materials, 2020, 30 : 3410 - 3417
  • [44] Green Synthesis, Structural, In Vitro and In Vivo Bioactivity Properties of ZnO Nanoparticles for Biomedical Applications
    Ibrahim, Essam H.
    Albulym, Obaid
    Kaygili, Omer
    Kilany, Mona
    Shkir, Mohd
    Hussien, Mai S. A.
    Bulut, Niyazi
    Zahran, H. Y.
    Yahia, I. S.
    JOURNAL OF BIOMATERIALS AND TISSUE ENGINEERING, 2019, 9 (06) : 731 - 738
  • [45] Harmonizing nature and nanotechnology: Phytoextract-mediated synthesis of Ag-doped ZnO nanoparticles using Lavandula stoechas extract for environmental and biomedical applications
    Kiani, Zahra
    Mirjalili, Seyedsina
    Heydaryan, Kamran
    Mohammadparast, Pouria
    Aramjoo, Hamed
    Bahraini, Fatemeh
    Yousefinia, Ali
    Torabi, Mohammadamin
    Ghoreishi, Seyedeh Masoumeh
    Fattahi, Mehdi
    Mortazavi-Derazkola, Sobhan
    JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2024, 96
  • [46] Superior Antimicrobial Activity of Ag-ZnO Bimetallic Nanoparticles Synthesised Using Hemigraphis colorata (Blume) Over ZnO Nanoparticles in Free and Collagen Coated form Against Wound Pathogens
    Mohanan, Deepa Pulickal
    Thazhenandayipurath, Vipina Vinod
    Sreekanth, K.
    Stanley, Jos V.
    Mathew, Divya
    Radhakrishnan, N.
    Krishnankutty, Radhakrishnan Edayileveettil
    JOURNAL OF CLUSTER SCIENCE, 2024, : 3065 - 3079
  • [47] Facile synthesis of Ag-ZnO core-shell nanostructures with enhanced photocatalytic activity
    Kadam, A. N.
    Bhopate, D. P.
    Kondalkar, V. V.
    Majhi, S. M.
    Bathula, C. D.
    Anh-Vy Tran
    Lee, Sang-Wha
    JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, 2018, 61 : 78 - 86
  • [48] Synthesis and hydrogen evolution reaction of nanosized Ag-ZnO coated MoS2
    Sun, Hai
    Liu, Hao
    Nie, Ming
    Zhao, Zuzhen
    Xue, Zhenhong
    Liao, Jianming
    Xue, Fengjuan
    Zhang, Shoumo
    Wu, Mingyu
    Gao, Tong
    CERAMICS INTERNATIONAL, 2021, 47 (10) : 13994 - 14000
  • [49] Synthesis of Ni-Ag-ZnO solid solution nanoparticles for photoreduction and antimicrobial applications
    Naseer, Sania
    Aamir, Muhammad
    Mirza, Muhammad Aslam
    Jabeen, Uzma
    Tahir, Raja
    Malghani, Muhammad Najam Khan
    Wali, Qamar
    RSC ADVANCES, 2022, 12 (13) : 7661 - 7670
  • [50] Synergistic Adsorption and Photocatalytic Activity under Visible Irradiation Using Ag-ZnO/GO Nanoparticles Derived at Low Temperature
    Viet Ha Tran Thi
    The Ha Cao
    Tri Nhut Pham
    Tien Thanh Pham
    Manh Cuong Le
    JOURNAL OF CHEMISTRY, 2019, 2019
12345