Study of metallo--lactamase production in clinical isolates of Pseudomonas aeruginosa

被引：0
|
作者：
Agrawal, G. [1 ]
Lodhi, R. B. [1 ]
Kamalakar, U. P. [1 ]
Khadse, R. K. [1 ]
Jalgaonkar, S. V. [1 ]
机构：
[1] Indira Gandhi Govt Med Coll, Dept Microbiol, Nagpur 444018, Maharashtra, India
来源：
INDIAN JOURNAL OF MEDICAL MICROBIOLOGY | 2008年 / 26卷 / 04期
关键词：
Metallo--lactamase; Pseudomonas aeruginosa; ceftazidime; imipenem;
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
A study of metallo--lactamase (MBL) production was done in clinical isolates of Pseudomonas aeruginosa. Isolates resistant to ceftazidime and imipenem were screened for MBL production by double disc synergy test (DDST) and minimum inhibitory concentration reduction test. There was complete correlation between two methods for imipenem. For ceftazidime, there was correlation between the two methods in all except four strains. In the screening test for MBL, ceftazidime - EDTA combination was better than imipenem - EDTA combination. 8.05 strains were MBL producers. Presence of MBL producer P. aeruginosa is a cause of concern. Simple DDST can be helpful for monitoring of these emerging resistant determinants.
引用
收藏
页码：349 / 351
页数：3
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