Triterpene saponins from the roots of Bupleurum spinosum Gouan

被引：2

作者：

Dahmoune, Amina ^{[1
,2
]}

Smati, Dalila ^{[3
]}

Mitaine-Offer, Anne-Claire ^{[1
]}

Miyamoto, Tomofumi ^{[4
]}

Tanaka, Chiaki ^{[4
]}

Paululat, Thomas ^{[5
]}

Lacaille-Dubois, Marie-Aleth ^{[1
]}

机构：

[1] Univ Bourgogne Franche Comte, Lab Pharmacognosie, PEPITE EA 4267, UFR Sci Sante, BP 87900, F-21079 Dijon, France

[2] Univ Mouloud Mammeri, Fac Med, Tizi Ouzou, Algeria

[3] Univ Alger, Fac Med, Dept Pharm, Algiers, Algeria

[4] Kyushu Univ, Grad Sch Pharmaceut Sci, Fukuoka 8128582, Japan

[5] Univ Siegen, Organ Chem 2, Nat Wissensch Tech Fak, D-57076 Siegen, Germany

来源：

PHYTOCHEMISTRY LETTERS | 2020年 / 39卷

关键词：

Bupleurum spinosum; Apiaceae; Triterpene saponins; NMR spectroscopy; SAIKOSAPONINS;

D O I：

10.1016/j.phytol.2020.08.007

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Three previously undescribed triterpene saponins, and four known ones, were isolated from the EtOH/H2O extract of the roots of Bupleurum spinosum. Their structures were characterized using spectroscopic techniques including 1D and 2D NMR (H-1, C-13, COSY, TOCSY, ROESY, HSQC, and HMBC) experiments and mass spectrometry as 3-O-beta-D-glucopyranosyl-(1 -> 6)-[beta-D-glucopyranosyl-(1 -> 2)]-[alpha-L-rhamnopyranosyl-(1 -> 4)]-beta-D-glucopyranosyl-3 beta,16 beta,23,28-tetrahydroxyolean-12-ene, 3-O-beta-D-glucopyranosyl-(1 -> 6)-[beta-D-glucopyranosyl-(1 -> 2)]-[alpha-L-rhamnopyranosyl-(1 -> 4)]-beta-D-glucopyranosyl-3 beta,16 beta,28-trihydroxy-23-oxoolean-12-ene, 3-O-beta-D-glucopyranosyl-(1 -> 6)-[alpha-L-rhamnopyranosyl(1 -> 4)]-beta-D-glucopyranosyl-3 beta,16 beta,28-trihydroxyolean-12-ene-23-oic-acid. The chemotaxonomic significance is underlined.

引用

页码：157 / 161

页数：5

共 50 条

[1] Saikosaponins from roots of Bupleurum gibraltaricum and Bupleurum spinosum
Barrero, AF
Haïdour, A
Sedqui, A
Ibn Mansour, A
Rodríguez-García, I
López, A
Muñoz-Dorado, M
[J]. PHYTOCHEMISTRY, 2000, 54 (08) : 741 - 745
[2] Four new triterpene saponins from Bupleurum rigidum L.
Chelghoum, Mustapha
Smati, Dalila
Mitaine-Offer, Anne-Claire
Paululat, Thomas
Lacaille-Dubois, Marie-Aleth
[J]. PHYTOCHEMISTRY LETTERS, 2018, 27 : 223 - 228
[3] BIOLOGICALLY-ACTIVE TRITERPENE SAPONINS FROM BUPLEURUM-FRUTICOSUM
GUINEA, MC
PARELLADA, J
LACAILLEDUBOIS, MA
WAGNER, H
[J]. PLANTA MEDICA, 1994, 60 (02) : 163 - 167
[4] Triterpene saponins from the roots of Achyranthes bidentata
Marouf, A
Desbene, S
Khanh, TC
Wagner, H
Correia, M
Chauffert, B
Lacaille-Dubois, MA
[J]. PHARMACEUTICAL BIOLOGY, 2001, 39 (04) : 263 - 267
[5] Triterpene saponins from the roots of Medicago hybrida
Bialy, Z
Jurzysta, M
Mella, M
Tava, A
[J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2006, 54 (07) : 2520 - 2526
[6] Triterpene saponins from the roots of Ilex pubescens
Zhou, Yuan
Zeng, Kewu
Zhang, Jiayu
Li, Ning
Chai, Xingyun
Jiang, Yong
Tu, Pengfei
[J]. FITOTERAPIA, 2014, 97 : 98 - 104
[7] Triterpene saponins from the roots of Clematis chinensis
Mimaki, Y
Yokosuka, A
Hamanaka, M
Sakuma, C
Yamori, T
Sashida, Y
[J]. JOURNAL OF NATURAL PRODUCTS, 2004, 67 (09): : 1511 - 1516
[8] Triterpene Saponins from the Roots of Ilex asprella
Lei, Yu
Shi, She-Po
Song, Yue-Lin
Bi, Dan
Tu, Peng-Fei
[J]. CHEMISTRY & BIODIVERSITY, 2014, 11 (05) : 767 - 775
[9] Four new triterpenoid saponins from the roots of Bupleurum rigidum
Sánchez-Contreras, S
Díaz-Lanza, AM
Bernabé, M
[J]. JOURNAL OF NATURAL PRODUCTS, 2000, 63 (11): : 1479 - 1482
[10] Oleanolic Triterpene Saponins from the Roots of Panax bipinnatifidus
Nguyen Huu Tung
Tran Hong Quang
Nguyen Thi Thanh Ngan
Chau Van Minh
Bui Kim Anh
Pham Quoc Long
Nguyen Manh Cuong
Kim, Young Ho
[J]. CHEMICAL & PHARMACEUTICAL BULLETIN, 2011, 59 (11) : 1417 - 1420

← 1 2 3 4 5 →