Synthesis of Novel Functionalized Triphenylphosphanylidene-Spirobarbiturates through a Three-Component Reaction

被引：6
|
作者：
Gupta, Shruti [1 ]
Aggarwal, Komal [1 ]
Khurana, Jitender M. [1 ]
机构：
[1] Univ Delhi, Dept Chem, New Delhi 110007, India
来源：
CHEMISTRYSELECT | 2018年 / 3卷 / 15期
关键词：
1,3-dipolar addition; pyrimidine; spiro; triphenyl phosphine; ylide; ONE-POT SYNTHESIS; BIOLOGICAL EVALUATION; CONVENIENT SYNTHESIS; DERIVATIVES; INHIBITORS; AGENTS; EFFICIENT;
D O I：
10.1002/slct.201800264
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Synthesis of novel functionalized triphenylphosphanylidene-7,9-diazaspiro[4.5]dec-1-ene-2-carboxylates has been reported by one-pot three component reactions of triphenyl phosphine, dialkyl acetylene dicarboxylates, and 5-arylidene-1,3-dimethylpyrimidine-2,4,6-triones in THF at room temperature. The products are obtained in high yields and have been fully characterized. The structure has been further confirmed by X-ray analysis of single crystal of one of the compounds.
引用
收藏
页码：4110 / 4113
页数：4
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