The upsurge in the need of targeted controlled drug delivery ( TCDD) has led to the invention of remarkable biomaterials with improved biocompatibility and biodegradability. In recent years, "Smart Polymers" have emerged as a potential candidate, competing with the existing hydrogel systems used for controlled drug delivery. This article is an effort to highlight the diverse applications of hydrogels for revolutionizing the present research on drug delivery systems. This article summarizes the role of hydrogels as delivery vehicles for drugs used in various disorders related to the brain and other distinct parts of the human body. The clinical application and toxicological aspects of hydrogels are also highlighted. Their potential for diagnostics and various therapeutic interventions against tuberculosis have been reviewed. In addition, the limitations and future prospectives in the development of biopolymeric hydrogels are discussed.
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Massachusetts Gen Hosp, Wellman Ctr Photomed, Boston, MA 02114 USA
Harvard Med Sch, Dept Dermatol, Boston, MA 02115 USA
Univ Johannesburg, Laser Res Ctr, Fac Hlth Sci, ZA-2028 Doornfontein, South AfricaNorth Khorasan Univ Med Sci, Dept Adv Sci & Technol, Bojnurd, Iran
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Poznan Univ Med Sci, Chair & Dept Pharmaceut Technol, PL-60780 Poznan, PolandPoznan Univ Med Sci, Chair & Dept Pharmaceut Technol, PL-60780 Poznan, Poland
Osmalek, Tomasz
Froelich, Anna
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Poznan Univ Med Sci, Chair & Dept Pharmaceut Technol, PL-60780 Poznan, PolandPoznan Univ Med Sci, Chair & Dept Pharmaceut Technol, PL-60780 Poznan, Poland
Froelich, Anna
Jadach, Barbara
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Poznan Univ Med Sci, Chair & Dept Pharmaceut Technol, PL-60780 Poznan, PolandPoznan Univ Med Sci, Chair & Dept Pharmaceut Technol, PL-60780 Poznan, Poland
Jadach, Barbara
Tatarek, Adam
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Poznan Univ Med Sci, Chair & Dept Pharmaceut Technol, PL-60780 Poznan, PolandPoznan Univ Med Sci, Chair & Dept Pharmaceut Technol, PL-60780 Poznan, Poland
Tatarek, Adam
Gadzinski, Piotr
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Poznan Univ Med Sci, Chair & Dept Pharmaceut Technol, PL-60780 Poznan, PolandPoznan Univ Med Sci, Chair & Dept Pharmaceut Technol, PL-60780 Poznan, Poland
Gadzinski, Piotr
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Falana, Aleksandra
Gralinska, Kinga
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Poznan Univ Med Sci, Chair & Dept Pharmaceut Technol, PL-60780 Poznan, PolandPoznan Univ Med Sci, Chair & Dept Pharmaceut Technol, PL-60780 Poznan, Poland
Gralinska, Kinga
Ekert, Michal
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Poznan Univ Med Sci, Chair & Dept Pharmaceut Technol, PL-60780 Poznan, PolandPoznan Univ Med Sci, Chair & Dept Pharmaceut Technol, PL-60780 Poznan, Poland
Ekert, Michal
Puri, Vinam
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Rutgers State Univ, Ernest Mario Sch Pharm, Dept Pharmaceut, New Jersey Ctr Biomat, William Levine Hall,Life Sci Bldg, Piscataway, NJ 08854 USAPoznan Univ Med Sci, Chair & Dept Pharmaceut Technol, PL-60780 Poznan, Poland
Puri, Vinam
Wrotynska-Barczynska, Joanna
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Poznan Univ Med Sci, Dept Gynecol Obstet & Gynecol Oncol, Div Infertil & Reprod Endocrinol, 33 Polna St, PL-60535 Poznan, PolandPoznan Univ Med Sci, Chair & Dept Pharmaceut Technol, PL-60780 Poznan, Poland
Wrotynska-Barczynska, Joanna
Michniak-Kohn, Bozena
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Rutgers State Univ, Ernest Mario Sch Pharm, Dept Pharmaceut, New Jersey Ctr Biomat, William Levine Hall,Life Sci Bldg, Piscataway, NJ 08854 USAPoznan Univ Med Sci, Chair & Dept Pharmaceut Technol, PL-60780 Poznan, Poland
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Delhi Pharmaceut Sci & Res Univ, Delhi Inst Pharmaceut Sci & Res DIPSAR, Dept Pharmaceut, New Delhi 110017, IndiaDelhi Pharmaceut Sci & Res Univ, Delhi Inst Pharmaceut Sci & Res DIPSAR, Dept Pharmaceut, New Delhi 110017, India
Paroha, Shweta
Verma, Juhi
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Natl Inst Immunol, Prod Dev Cell, Aruna Asaf Ali Marg, New Delhi 110067, IndiaDelhi Pharmaceut Sci & Res Univ, Delhi Inst Pharmaceut Sci & Res DIPSAR, Dept Pharmaceut, New Delhi 110017, India
Verma, Juhi
Dubey, Ravindra Dhar
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Invictus Oncol Pvt Ltd, Patparganj Ind Area, New Delhi 110092, IndiaDelhi Pharmaceut Sci & Res Univ, Delhi Inst Pharmaceut Sci & Res DIPSAR, Dept Pharmaceut, New Delhi 110017, India
Dubey, Ravindra Dhar
Dewangan, Rikeshwer Prasad
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Jamia Hamdard, Dept Pharmaceut Chem, Sch Pharmaceut Educ & Res, New Delhi 110062, IndiaDelhi Pharmaceut Sci & Res Univ, Delhi Inst Pharmaceut Sci & Res DIPSAR, Dept Pharmaceut, New Delhi 110017, India
Dewangan, Rikeshwer Prasad
Molugulu, Nagashekhara
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Monash Univ, Sch Pharm, Jalan Lagoon Selatan, Bandar Sunway 47500, Selangor, MalaysiaDelhi Pharmaceut Sci & Res Univ, Delhi Inst Pharmaceut Sci & Res DIPSAR, Dept Pharmaceut, New Delhi 110017, India
Molugulu, Nagashekhara
Bapat, Ranjeet A.
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Int Med Univ, Sch Dent, Div Clin Dent, Kuala Lumpur 57000, MalaysiaDelhi Pharmaceut Sci & Res Univ, Delhi Inst Pharmaceut Sci & Res DIPSAR, Dept Pharmaceut, New Delhi 110017, India
Bapat, Ranjeet A.
Sahoo, Pravat Kumar
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Delhi Pharmaceut Sci & Res Univ, Delhi Inst Pharmaceut Sci & Res DIPSAR, Dept Pharmaceut, New Delhi 110017, IndiaDelhi Pharmaceut Sci & Res Univ, Delhi Inst Pharmaceut Sci & Res DIPSAR, Dept Pharmaceut, New Delhi 110017, India
Sahoo, Pravat Kumar
Kesharwani, Prashant
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Jamia Hamdard, Dept Pharmaceut, Sch Pharmaceut Educ & Res, New Delhi 110062, IndiaDelhi Pharmaceut Sci & Res Univ, Delhi Inst Pharmaceut Sci & Res DIPSAR, Dept Pharmaceut, New Delhi 110017, India