Comparison of myelin water fraction values in periventricular white matter lesions between multiple sclerosis and neuromyelitis optica spectrum disorder

被引：24
|
作者：
Jeong, In Hye [1 ]
Choi, Joon Yul [2 ]
Kim, Su-Hyun [1 ]
Hyun, Jae-Won [1 ]
Joung, AeRan [1 ]
Lee, Jongho [2 ]
Kim, Ho Jin [1 ]
机构：
[1] Natl Canc Ctr, Res Inst & Hosp, Dept Neurol, 323 Ilsan St, Goyang Si 410769, Gyeonggi Do, South Korea
[2] Seoul Natl Univ, Dept Elect & Comp Engn, Bldg 301,Room 1008,1 Gwanak Ro, Seoul 08826, South Korea
来源：
MULTIPLE SCLEROSIS JOURNAL | 2016年 / 22卷 / 12期
关键词：
Myelin water imaging; multiple sclerosis; neuromyelitis optica spectrum disorder; demyelination; BRAIN-LESIONS; DEMYELINATION; PATHOLOGY;
D O I：
10.1177/1352458516636247
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) are inflammatory autoimmune diseases of the central nervous system. We hypothesized that the degree of demyelination within lesions in MS and NMOSD would differ as the pathophysiology of the two diseases do. We used myelin water imaging to compare the myelin water fraction (MWF) in 106 periventricular white matter (PVWM) lesions in 27 MS patients and 51 PVWM lesions in 20 NMOSD patients. The MWF was significantly reduced in the MS compared with the NMOSD lesions, suggesting that myelin loss was more severe in MS than in NMOSD.
引用
收藏
页码：1616 / 1620
页数：5
相关论文
共 50 条
  • [21] Difference in fatigue and pain between neuromyelitis optica spectrum disorder and multiple sclerosis
    Masuda, Hiroki
    Mori, Masahiro
    Uzawa, Akiyuki
    Uchida, Tomohiko
    Ohtani, Ryohei
    Kuwabara, Satoshi
    PLOS ONE, 2020, 15 (04):
  • [22] Cognitive impairment differs between neuromyelitis optica spectrum disorder and multiple sclerosis
    Kim, Su-Hyun
    Kwak, Kichang
    Jeong, In Hye
    Hyun, Jae-Won
    Jo, Hyo-Jin
    Joung, AeRan
    Yu, Eun-Seung
    Kim, Ji-Hee
    Lee, Sang Hyun
    Yun, Sooin
    Joo, Jungnam
    Lee, Dong-kyun
    Lee, Jong-Min
    Kim, Ho Jin
    MULTIPLE SCLEROSIS JOURNAL, 2016, 22 (14) : 1850 - 1858
  • [23] Accelerated myelin water imaging for assessment of cervical spinal cord demyelination in multiple sclerosis and neuromyelitis optica spectrum disorder
    Dvorak, A.
    Ljungberg, E.
    Vavasour, I. M.
    Liu, H.
    Rauscher, A.
    Kramer, J.
    Laule, C.
    MacKay, A. L.
    Traboulsee, A. L.
    Kozlowski, P.
    Kolind, S. H.
    MULTIPLE SCLEROSIS JOURNAL, 2017, 23 : 796 - 797
  • [24] Myelin and total water content show similar distributions in neuromyelitis optica and multiple sclerosis lesions
    Soares, A. B.
    Vavasour, I. M.
    Combes, A.
    Meyers, S. M.
    Manogaran, P.
    Xiao, S.
    Wurl, A.
    Li, D. K. B.
    Traboulsee, A. L.
    Kolind, S. H.
    MULTIPLE SCLEROSIS JOURNAL, 2017, 23 : 806 - 806
  • [25] Comparison of cognitive function and brain MRI profiles between neuromyelitis optica spectrum disorder and multiple sclerosis
    Ashtari, Fereshteh
    Najarzadeh, Pouran
    MULTIPLE SCLEROSIS JOURNAL, 2023, 29 : 754 - 754
  • [26] A comparison of cognitive performances between neuromyelitis optica spectrum disorder and multiple sclerosis patients in Indian context
    Swati Kumar
    Goutam Gangopadhyay
    Atanu Biswas
    Souvik Dubey
    Alak Pandit
    Shambaditya Das
    Biman Kanti Ray
    The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 57
  • [27] A comparison of cognitive performances between neuromyelitis optica spectrum disorder and multiple sclerosis patients in Indian context
    Kumar, Swati
    Gangopadhyay, Goutam
    Biswas, Atanu
    Dubey, Souvik
    Pandit, Alak
    Das, Shambaditya
    Ray, Biman Kanti
    EGYPTIAN JOURNAL OF NEUROLOGY PSYCHIATRY AND NEUROSURGERY, 2021, 57 (01):
  • [28] Neuromyelitis optica spectrum disorder and multiple sclerosis in a Sardinian family
    Gelibter, S.
    Mazzi, B.
    Tassara, M.
    Colombo, B.
    Guerrieri, S.
    Giordano, A.
    Preziosa, P.
    Comola, M.
    Esposito, F.
    Martinelli, V.
    Rocca, M. A.
    Comi, G.
    Leocani, L.
    Martinelli-Boneschi, F.
    MULTIPLE SCLEROSIS AND RELATED DISORDERS, 2018, 25 : 73 - 76
  • [29] The risk of dementia in multiple sclerosis and neuromyelitis optica spectrum disorder
    Cho, Eun Bin
    Jung, Se Young
    Jung, Jin-Hyung
    Yeo, Yohwan
    Kim, Hee Jin
    Han, Kyungdo
    Shin, Dong Wook
    Min, Ju-Hong
    FRONTIERS IN NEUROSCIENCE, 2023, 17
  • [30] Diffusion tensor imaging of normal-appearing white matter in patients with neuromyelitis optica spectrum disorder and multiple sclerosis
    Kim, S. -H.
    Kwak, K.
    Hyun, J. -W.
    Joung, A.
    Lee, S. H.
    Choi, Y. -H.
    Lee, J. -M.
    Kim, H. J.
    EUROPEAN JOURNAL OF NEUROLOGY, 2017, 24 (07) : 966 - 973
12345