Regulated intratumoral expression of IL-12 in combination with cytotoxic agents as a strategy for the treatment of metastatic breast cancer

被引:0
|
作者
Nemunaitis, J.
McArthur, H.
Hudis, C.
Reed, T.
Broder, S.
Lebel, F.
Barrett, J.
Lewis, J.
Norton, L.
机构
关键词
D O I
10.1158/0008-5472.SABCS13-P5-02-01
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
P5-02-01
引用
收藏
页数:2
相关论文
共 50 条
  • [21] Intratumoral IL-12 and TNF-α-loaded microspheres lead to regression of breast cancer and systemic antitumor immunity
    Sabel, MS
    Skitzki, J
    Stoolman, L
    Egilmez, NK
    Mathiowitz, E
    Bailey, N
    Chang, WJ
    Chang, AE
    ANNALS OF SURGICAL ONCOLOGY, 2004, 11 (02) : 147 - 156
  • [22] Intratumoral IL-12 and TNF-α–Loaded Microspheres Lead To Regression of Breast Cancer and Systemic Antitumor Immunity
    Michael S. Sabel
    Joseph Skitzki
    Lloyd Stoolman
    Nejat K. Egilmez
    Edith Mathiowitz
    Nicola Bailey
    Wen-Jian Chang
    Alfred E. Chang
    Annals of Surgical Oncology, 2004, 11 : 147 - 156
  • [23] Serum IL-8 and IL-12 levels in breast cancer
    Duygu Derin
    Hilal Oguz Soydinc
    Nese Guney
    Faruk Tas
    Hakan Camlica
    Derya Duranyildiz
    Vildan Yasasever
    Erkan Topuz
    Medical Oncology, 2007, 24 : 163 - 168
  • [24] Serum IL-8 and IL-12 levels in breast cancer
    Derin, Duygu
    Soydinc, Hilal Oguz
    Guney, Nese
    Tas, Faruk
    Camlica, Hakan
    Duranyildiz, Derya
    Yasasever, Vildan
    Topuz, Erkan
    MEDICAL ONCOLOGY, 2007, 24 (02) : 163 - 168
  • [25] Combination of intratumoral regulated IL-12 gene delivery and systemic chemotherapy with Palifosfamide (IPM-Tris) enhances anti-tumor effects in breast cancer (4T1) model
    Murugesan, Selva
    Fogler, William
    Valacer, David
    Youssoufian, Hagop
    Morgan, Robert A.
    Herberman, Ronald
    Connelly, Shelia
    Hart, Susan E.
    Bharathan, Mini
    Chan, Timothy
    Shakleya, Diaa
    Moreno, Mario
    Barrett, John A.
    CANCER RESEARCH, 2012, 72
  • [26] Combination treatment for metastatic breast cancer
    Tanday, Sanjay
    LANCET ONCOLOGY, 2012, 13 (09): : E374 - E374
  • [27] Treatment of spontaneous canine mast cell tumors by electrochemotherapy combined with IL-12 gene electrotransfer: Comparison of intratumoral and peritumoral application of IL-12
    Tratar, Ursa Lampreht
    Milevoj, Nina
    Cemazar, Maja
    Znidar, Katarina
    Valentinuzzi, Katja Ursic
    Brozic, Andreja
    Tomsic, Katerina
    Sersa, Gregor
    Tozon, Natasa
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2023, 120
  • [28] ADENOVIRUS IL-12 AND DOCETAXEL IN COMBINATION WITH ANTI-PD1 AS AN EFFECTIVE TREATMENT STRATEGY FOR TNBC
    Qian, Wei
    Zhou, Jianying
    Rosato, Roberto
    Chang, Jenny
    Anselme, Ann
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2020, 8 : A266 - A266
  • [29] Intratumoral delivery of IL-12 and IL-27 mRNA using lipid nanoparticles for cancer immunotherapy
    Liu, Jin-Qing
    Zhang, Chengxiang
    Zhang, Xinfu
    Yan, Jingyue
    Zeng, Chunxi
    Talebian, Fatemeh
    Lynch, Kimberly
    Zhao, Weiyu
    Hou, Xucheng
    Du, Shi
    Kang, Diana D.
    Deng, Binbin
    McComb, David W.
    Bai, Xue-Feng
    Dong, Yizhou
    JOURNAL OF CONTROLLED RELEASE, 2022, 345 : 306 - 313
  • [30] Cytokine expression by murine DX5+ cells in response to IL-12, IL-18, or the combination of IL-12 and IL-18
    Chakir, H
    Lemay, AM
    Webb, JR
    CELLULAR IMMUNOLOGY, 2001, 212 (01) : 71 - 81