Synthesis of novel quaternary chitosan derivatives via N-chloroacyl-6-O-triphenylmethylchitosans

被引：39
|
作者：
Holappa, J
Nevalainen, T
Soininen, P
Másson, M
Järvinen, T
机构：
[1] Univ Kuopio, Dept Pharmaceut Chem, FIN-70211 Kuopio, Finland
[2] Univ Kuopio, Dept Chem, FIN-70211 Kuopio, Finland
[3] Univ Iceland, Fac Pharm, IS-107 Reykjavik, Iceland
来源：
BIOMACROMOLECULES | 2006年 / 7卷 / 02期
关键词：
D O I：
10.1021/bm050707j
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Various quaternary chitosan derivative structures were synthesized by reacting N-chloroacyl-6-O-triphenylmethy-1-chitosans with tertiary an-tines. Full substitutions were obtained from the quaternization reactions and the obtained water-soluble quaternary chitosan derivatives were thoroughly characterized with H-1 NMR, C-13 NMR, H-1-C-13 HSQC NMR, and FT-IR.
引用
收藏
页码：407 / 410
页数：4
相关论文
共 50 条
  • [41] Synthesis of 6-N,N,N-Trimethyltriazole Chitosan via "Click Chemistry" and Evaluation for Gene Delivery
    Gao, Yu
    Zhang, Zhiwen
    Chen, Lingli
    Gu, Wangwen
    Li, Yaping
    BIOMACROMOLECULES, 2009, 10 (08) : 2175 - 2182
  • [42] Synthesis and Antibacterial Activity of Novel Quaternary Ammonium Pyridoxine Derivatives
    Shtyrlin, Nikita V.
    Sapozhnikov, Sergey V.
    Koshkin, Sergey A.
    Iksanova, Alfiya G.
    Sabirov, Arthur H.
    Kayumov, Airat R.
    Nureeva, Aliya A.
    Zeldi, Marina I.
    Shtyrlin, Yurii G.
    MEDICINAL CHEMISTRY, 2015, 11 (07) : 656 - 665
  • [43] Synthesis and antibacterial activity of novel 6-O-substituted erythromycin A derivatives
    Clark, RF
    Ma, ZK
    Wang, SY
    Griesgraber, G
    Tufano, M
    Yong, H
    Li, LP
    Zhang, XL
    Nilius, AM
    Chu, DTW
    Or, YS
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2000, 10 (08) : 815 - 819
  • [44] Synthesis and antimalarial activity of novel N6-substituted adenosine derivatives
    Heidler, PH
    Herforth, C
    Link, A
    NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2003, 22 (5-8): : 977 - 979
  • [45] Synthesis, Characterization, and Drug-Release Behavior of Amphiphilic Quaternary Ammonium Chitosan Derivatives
    Zhang, Aidi
    Ding, Derun
    Ren, Jicun
    Zhu, Xiangli
    Yao, Youhong
    JOURNAL OF APPLIED POLYMER SCIENCE, 2014, 131 (04)
  • [46] QUATERNARY AMINO-SUGARS - SYNTHESIS AND CHARACTERIZATION OF QUATERNARY AMMONIUM-SALTS OF N-SUBSTITUTED DERIVATIVES OF 6-AMINO-6-DEOXY-1,2-O-ISOPROPYLIDENE-ALPHA-D-GLUCOFURANOSE
    SHARMA, L
    SINGH, S
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1994, 33 (09): : 851 - 854
  • [47] Synthesis, structure, and properties of N-2-hydroxylpropyl-3-trimethylammonium-O-carboxymethyl chitosan derivatives
    Liu, Qun
    Chen, Jialiang
    Yang, Xiaodeng
    Qiao, Congde
    Li, Zhi
    Xu, Chunlin
    Li, Yan
    Chai, Jinling
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 144 (144) : 568 - 577
  • [48] Homogeneous graft copolymerization of chitosan with butyl acrylate by γ-irradiation via a 6-O-maleoyl-N-phthaloyl-chitosan intermediate
    Huang, Meifang
    Xia, Xu
    Zhang, Zhongcheng
    Liu, Li
    Fang, Yue'e
    JOURNAL OF APPLIED POLYMER SCIENCE, 2006, 102 (01) : 489 - 493
  • [49] Synthesis of novel N-acyl thiolated chitosan derivatives and their assessment for toxicity and antimicrobial activity in vitro
    Sonone, Swapneel
    Narkhede, Harshal
    Shirote, Pramod
    Naikwade, Nilofer
    ORIENTAL JOURNAL OF CHEMISTRY, 2010, 26 (03) : 1073 - 1077
  • [50] POLY 169-Synthesis and chemoselectivity of novel methylated N-benzyl chitosan derivatives with iodomethane
    Sajomsang, Warayuth
    Tantayanon, Supawan
    Daly, William H.
    Tangpasuthadol, Varawut
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2006, 232
12345