QUATERNARY AMINO-SUGARS - SYNTHESIS AND CHARACTERIZATION OF QUATERNARY AMMONIUM-SALTS OF N-SUBSTITUTED DERIVATIVES OF 6-AMINO-6-DEOXY-1,2-O-ISOPROPYLIDENE-ALPHA-D-GLUCOFURANOSE

被引：0

作者：

SHARMA, L ^{[1
]}

SINGH, S ^{[1
]}

机构：

[1] GURU NANAK DEV UNIV, DEPT CHEM, AMRITSAR 143005, PUNJAB, INDIA

来源：

INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 1994年 / 33卷 / 09期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Coupling of secondary amines viz. dimethylamine, diethylamine and diisopropylamine with 5,6-anhydro-1,2-O-isopropylidene-alpha-D-glucofuranose (1) afford amino sugars, 2, 3 and 4, having a tertiary amino group linked to carbon-6 of glucose moiety. Quaternization of 2, 3 and 4 with methyl iodide yield title compounds 5, 6 and 8 in quantitative yield. Likewise, 7 has been synthesized in 60% yield by reaction of 3 with benzyl chloride.

引用

页码：851 / 854

页数：4

共 41 条

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