The anti-EGFR antibody mixture Sym004 overcomes acquired resistance to cetuximab in colorectal cancer

被引：0
|
作者：
Sanchez-Martin, Francisco J.
Dalmases, Alba
Bellosillo, Beatriz
Argiles, Guillem
Gelabert, Mariona
Canadas, Israel
Vidal, Joana
Siravegna, Giulia
Arena, Sabrina
Koefoed, Klaus
Visa, Laura
Arpf, Oriol
Horak, Ivan D.
Iglesias, Mar
Stroh, Christopher
Kragh, Michael
Rovira, Ana
Albanell, Joan
Bardelli, Alberto
Tabernero, Josep
Montagut, Clara
机构：
来源：
CANCER RESEARCH | 2016年 / 76卷
关键词：
D O I：
10.1158/1538-7445.AM2016-2149
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
2149
引用
收藏
页数：3
相关论文
共 50 条
  • [41] Mutational signatures impact the evolution of anti-EGFR antibody resistance in colorectal cancer
    Woolston, Andrew
    Barber, Louise J.
    Griffiths, Beatrice
    Pich, Oriol
    Lopez-Bigas, Nuria
    Matthews, Nik
    Rao, Sheela
    Watkins, David
    Chau, Ian
    Starling, Naureen
    Cunningham, David
    Gerlinger, Marco
    NATURE ECOLOGY & EVOLUTION, 2021, 5 (07) : 1024 - +
  • [42] Mutational signatures impact the evolution of anti-EGFR antibody resistance in colorectal cancer
    Andrew Woolston
    Louise J. Barber
    Beatrice Griffiths
    Oriol Pich
    Nuria Lopez-Bigas
    Nik Matthews
    Sheela Rao
    David Watkins
    Ian Chau
    Naureen Starling
    David Cunningham
    Marco Gerlinger
    Nature Ecology & Evolution, 2021, 5 : 1024 - 1032
  • [43] Mechanisms of resistance to anti-EGFR monoclonal antibody treatment in metastatic colorectal cancer
    Saridaki, Zacharenia
    Georgoulias, Vassilis
    Souglakos, John
    WORLD JOURNAL OF GASTROENTEROLOGY, 2010, 16 (10) : 1177 - 1187
  • [44] Anti-EGFR monoclonal antibody treatment in colorectal cancer
    Nature Clinical Practice Gastroenterology & Hepatology, 2005, 2 (6): : 249 - 250
  • [45] Epidermal growth factor receptor (EGFR) ubiquitination as a mechanism of acquired resistance escaping treatment by the Anti-EGFR monoclonal antibody cetuximab
    Lu, Yang
    Li, Xinqun
    Liang, Ke
    Luwor, Rodney
    Siddik, Zahid H.
    Nuiis, Gordon B.
    Mendelsohn, John
    Fan, Zhen
    CANCER RESEARCH, 2007, 67 (17) : 8240 - 8247
  • [46] Heterogeneity of Acquired Resistance to Anti-EGFR Monoclonal Antibodies in Patients with Metastatic Colorectal Cancer
    Pietrantonio, Filippo
    Vernieri, Claudio
    Siravegna, Giulia
    Mennitto, Alessia
    Berenato, Rosa
    Perrone, Federica
    Gloghini, Annunziata
    Tamborini, Elena
    Lonardi, Sara
    Morano, Federica
    Picciani, Benedetta
    Busico, Adele
    Volpi, Chiara Costanza
    Martinetti, Antonia
    Battaglin, Francesca
    Bossi, Ilaria
    Pellegrinelli, Alessio
    Milione, Massimo
    Cremolini, Chiara
    Di Bartolomeo, Maria
    Bardelli, Alberto
    de Braud, Filippo
    CLINICAL CANCER RESEARCH, 2017, 23 (10) : 2414 - 2422
  • [47] Overcoming the Hurdles: Surmounting Acquired Resistance to Anti-EGFR Therapy in Metastatic Colorectal Cancer
    Sackstein, Paul E.
    Chintapally, Nikita
    Wilgucki, Molly
    Hartley, Marion L.
    Alqahtani, Ali
    Weinberg, Benjamin A.
    CLINICAL ADVANCES IN HEMATOLOGY & ONCOLOGY, 2023, 21 (11) : 572 - 583
  • [48] The secondary mutation of KRAS and acquired resistance to anti-EGFR therapy in metastatic colorectal cancer
    Xia, X.
    Du, W.
    Zhu, Y.
    Bai, Y.
    Liu, M.
    CLINICAL & EXPERIMENTAL METASTASIS, 2017, 34 (3-4) : 218 - 218
  • [49] Sym004: A Novel Synergistic Anti-Epidermal Growth Factor Receptor Antibody Mixture with Superior Anticancer Efficacy
    Pedersen, Mikkel Wandahl
    Jacobsen, Helle Jane
    Koefoed, Klaus
    Hey, Adam
    Pyke, Charles
    Haurum, John Sorensen
    Kragh, Michael
    CANCER RESEARCH, 2010, 70 (02) : 588 - 597
  • [50] Molecular Characterization of Acquired Resistance To Anti-EGFR Monoclonal Antibodies in Colorectal Cancer Patients
    Bellosillo, Beatriz
    Dalmases, Alba
    Martinez, Alejandro
    Iglesias, Mar
    Gonzalez, Iria
    Salido, Marta
    Busto, Marcos
    Sanchez, Juan
    Vidal, Joana
    Clave, Sergi
    Moragon, Ester
    Pairet, Silvia
    Bellmunt, Joaquim
    Serrano, Sergio
    Rovira, Ana
    Albanell, Joan
    Montagut, Clara
    MODERN PATHOLOGY, 2015, 28 : 148A - 148A
12345