The anti-EGFR antibody mixture Sym004 overcomes acquired resistance to cetuximab in colorectal cancer

被引：0
|
作者：
Sanchez-Martin, Francisco J.
Dalmases, Alba
Bellosillo, Beatriz
Argiles, Guillem
Gelabert, Mariona
Canadas, Israel
Vidal, Joana
Siravegna, Giulia
Arena, Sabrina
Koefoed, Klaus
Visa, Laura
Arpf, Oriol
Horak, Ivan D.
Iglesias, Mar
Stroh, Christopher
Kragh, Michael
Rovira, Ana
Albanell, Joan
Bardelli, Alberto
Tabernero, Josep
Montagut, Clara
机构：
来源：
CANCER RESEARCH | 2016年 / 76卷
关键词：
D O I：
10.1158/1538-7445.AM2016-2149
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
2149
引用
收藏
页数：3
相关论文
共 50 条
  • [31] Targeting of colorectal cancer organoids with zoledronic acid conjugated to the anti-EGFR antibody cetuximab
    Benelli, Roberto
    Costa, Delfina
    Salvini, Laura
    Tardito, Samuele
    Tosetti, Francesca
    Villa, Federico
    Zocchi, Maria Raffaella
    Poggi, Alessandro
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 10 (12)
  • [32] Phase I dose-escalation trial of Sym004, a mixture of two anti-EGFR antibodies, in Japanese patients with advanced solid tumors.
    Kato, Ken
    Kojima, Takashi
    Yamazaki, Kentaro
    Muro, Kei
    Hara, Hiroki
    Chin, Keisho
    Goddemeier, Thomas
    Watanabe, Morihiro
    Doi, Toshihiko
    JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (15)
  • [33] Switching anti-EGFR antibody re-sensitizes head and neck cancer patient following acquired resistance to cetuximab
    Khattri, Arun
    Sheikh, Nizamuddin
    Agrawal, Nikhil
    Kaushik, Sandeep
    Kochanny, Sara
    Ginat, Daniel
    Lingen, Mark W.
    Blair, Elizabeth
    Seiwert, Tanguy Y.
    CANCER GENE THERAPY, 2024, 31 (10) : 1477 - 1485
  • [34] Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer
    Sandra Misale
    Rona Yaeger
    Sebastijan Hobor
    Elisa Scala
    Manickam Janakiraman
    David Liska
    Emanuele Valtorta
    Roberta Schiavo
    Michela Buscarino
    Giulia Siravegna
    Katia Bencardino
    Andrea Cercek
    Chin-Tung Chen
    Silvio Veronese
    Carlo Zanon
    Andrea Sartore-Bianchi
    Marcello Gambacorta
    Margherita Gallicchio
    Efsevia Vakiani
    Valentina Boscaro
    Enzo Medico
    Martin Weiser
    Salvatore Siena
    Federica Di Nicolantonio
    David Solit
    Alberto Bardelli
    Nature, 2012, 486 : 532 - 536
  • [35] Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer
    Misale, Sandra
    Yaeger, Rona
    Hobor, Sebastijan
    Scala, Elisa
    Janakiraman, Manickam
    Liska, David
    Valtorta, Emanuele
    Schiavo, Roberta
    Buscarino, Michela
    Siravegna, Giulia
    Bencardino, Katia
    Cercek, Andrea
    Chen, Chin-Tung
    Veronese, Silvio
    Zanon, Carlo
    Sartore-Bianchi, Andrea
    Gambacorta, Marcello
    Gallicchio, Margherita
    Vakiani, Efsevia
    Boscaro, Valentina
    Medico, Enzo
    Weiser, Martin
    Siena, Salvatore
    Di Nicolantonio, Federica
    Solit, David
    Bardelli, Alberto
    NATURE, 2012, 486 (7404) : 532 - U131
  • [36] Cetuximab. Anti-EGFR monoclonal antibody
    Etessami, A
    Bourhis, J
    DRUGS OF THE FUTURE, 2000, 25 (09) : 895 - 899
  • [37] Anti EGFR antibody (Cetuximab) in metastatic colorectal cancer
    Krause, M
    Baumann, M
    STRAHLENTHERAPIE UND ONKOLOGIE, 2004, 180 (11) : 742 - 743
  • [38] Targeting of tumour cells with acquired resistance to anti-EGFR antibody
    Khelwatty, Said A.
    Essapen, Sharadah
    Seddon, Alan M.
    Fan, Zhen
    Modjtahedi, Helmout
    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2015, 36 : S73 - S73
  • [39] Phase I trial of the first-in-class EGFR antibody mixture, Sym004, in patients with advanced solid tumors.
    Dienstmann, R.
    Tolcher, A. W.
    Papadopoulos, K. P.
    Rasco, D. W.
    Tabernero, J.
    Brana, I.
    Piera, A.
    Skartved, N. J.
    Aladdin, H.
    Petersen, J.
    Patnaik, A.
    JOURNAL OF CLINICAL ONCOLOGY, 2011, 29 (15)
  • [40] Mechanisms of resistance to anti-EGFR monoclonal antibody treatment in metastatic colorectal cancer
    Zacharenia Saridaki
    Vassilis Georgoulias
    John Souglakos
    World Journal of Gastroenterology, 2010, 16 (10) : 1177 - 1187
12345