Neurostimulation in the treatment of epilepsy

被引：46
|
作者：
Bergey, Gregory K. [1 ]
机构：
[1] Johns Hopkins Univ Hosp, Dept Neurol, Baltimore, MD 21287 USA
来源：
EXPERIMENTAL NEUROLOGY | 2013年 / 244卷
关键词：
Neurostimulation; Epilepsy; Anterior thalamic; Responsive neurostimulation; Closed loop; Vagus nerve stimulation; VAGUS NERVE-STIMULATION; DEEP-BRAIN-STIMULATION; CHRONIC CEREBELLAR STIMULATION; ELECTRICAL-STIMULATION; ANTERIOR NUCLEUS; RAT MODEL; SEIZURES; FREQUENCY; EFFICACY; ONSET;
D O I：
10.1016/j.expneurol.2013.04.004
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
There is increased interest in neurostimulation as a treatment for drug-resistant epilepsy. Two large pivotal trials have recently been completed, one using bilateral anterior thalamic stimulation and another employing closed loop responsive therapy of the brain. These are potential additions to the therapeutic options for neurostimulation in addition to already approved vagus nerve stimulation. This review will address the principles of the various types of neurostimulation, the results of the pivotal trials and the important considerations for interpreting the results of these trials which differ from trials of antiepileptic drugs. (C) 2013 Elsevier Inc. All rights reserved.
引用
收藏
页码：87 / 95
页数：9
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