Responsive Neurostimulation for the Treatment of Epilepsy

被引：25
|
作者：
Matias, Caio M. [1 ,2 ]
Sharan, Ashwini [1 ]
Wu, Chengyuan [1 ]
机构：
[1] Thomas Jefferson Univ Hosp, Dept Neurol Surg, 909 Walnut St,Third Floor, Philadelphia, PA 19107 USA
[2] Univ Sao Paulo, Ribeirao Preto Med Sch, Dept Surg & Anat, Ribeirao Preto, SP, Brazil
来源：
NEUROSURGERY CLINICS OF NORTH AMERICA | 2019年 / 30卷 / 02期
基金：
美国国家卫生研究院;
关键词：
Responsive stimulation; Closed-loop neurostimulation; Neuromodulation; Cortical stimulation; Partial seizures; Focal seizures; Focal stimulation; INTRAOPERATIVE COMPUTED-TOMOGRAPHY; QUALITY-OF-LIFE; BRAIN-STIMULATION; IMPLANTATION; PLACEMENT; REMISSION; ADULTS;
D O I：
10.1016/j.nec.2018.12.006
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
There are a significant number of patients with epilepsy who are drug-resistant and for whom resective procedures are not an option. For these patients, neuromodulation may be an option, including closed-loop stimulation, such as responsive neurostimulation (RNS). The RNS System is a programmable and responsive device that consists of leads, a pulse generator, and an external programmer. An algorithm detects specific patterns of epileptogenic activity and triggers focal stimulation to interrupt a seizure. RNS is an effective and safe adjunctive therapy that in addition to seizure frequency reduction may have other applications, such as drug-response evaluation and long-term electrocorticography recording.
引用
收藏
页码：231 / +
页数：13
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