A Novel Method of Mobilizing Leukemia Initiating Cells by a Small Molecule Cdc42 Activity-Specific Inhibitor (CASIN) for Acute Myeloid Leukemia Therapy

被引：0
|
作者：
Liu, Wei [1 ]
Mizukawa, Benjamin [2 ]
Wunderlich, Mark
Johnson, James F.
Mulloy, James C.
Zheng, Yi
机构：
[1] Cincinnati Childrens Hosp Med Ctr, Mol & Dev Biol Program, Div Expt Hematol & Canc Biol, Cincinnati, OH USA
[2] Cincinnati Childrens Hosp Med Ctr, Canc & Blood Dis Inst, Cincinnati, OH USA
来源：
BLOOD | 2009年 / 114卷 / 22期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
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页码：11 / 11
页数：1
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    Agostoni, V.
    Pule, M.
    Rousseau, R.
    Lawson, A.
    Finney, H.
    Biondi, A.
    Biagi, E.
    [J]. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2010, 95 : 305 - 305
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